Interferon-α2b spray inhalation did not shorten virus shedding time of SARS-CoV-2 in hospitalized patients: a preliminary matched case-control study

Interferon-α2b spray inhalation did not shorten virus shedding time of SARS-CoV-2 in hospitalized patients: a preliminary matched case-control study

Background: Interferon regulatory factor 6 functions (IRF6) exhibits tumor-suppression in multiple types of cancer. Here, the antitumor properties and pathways involved in the mechanism of IRF6 investigated in cervical cancer.


Methods: Forty-one pairs of cervical cancer specimens and para-carcinoma tissues were collected to evaluate IRF6 expression using immunohistochemical (IHC) staining and miR-587. Effects of miR-587 and IRF6 in the growth of cervical cancer cells explored by MTT test and HeLa tumor mouse xenograft model. Migration and invasion of cervical cancer cells are monitored using transwell test.


Results: Expression of IRF6 in cervical cancer specimens and cell lines were significantly reduced compared with a suitable control group. In addition, the IRF6 expression negatively correlated with miR-587 in cervical cancer tissue. Bioinformatics algorithms and luciferase tests revealed that IRF6 is a potential target of miR-587 and miR-587 mimic transfection cause significant suppression of the IRF6 protein levels in cervical cancer cells. We also found that the antineoplastic properties of IRF6 can be reversed by overexpressing miR-587 in cervical cancer cells. Upregulation of miR-587 correlated with poor overall survival in cervical cancer. In an experiment in vivo silencing of miR-587 induced tumor growth inhibition HeLa, which was associated with upregulation of IRF6 protein in the tumor.


Conclusion: miR-587 represses posttranscriptionally IRF6 protein expression to cancel the antineoplastic activity of IRF6. The miR-587 / IRF6 signaling pathway plays an important role in the development of cervical cancer and serve as a potential therapeutic target for the treatment of cervical cancer.

 Interferon-α2b spray inhalation did not shorten virus shedding time of SARS-CoV-2 in hospitalized patients: a preliminary matched case-control study
Interferon-α2b spray inhalation did not shorten virus shedding time of SARS-CoV-2 in hospitalized patients: a preliminary matched case-control study

a mouse model of SARS-CoV-2 expressing inflammatory role of type I interferon signaling

acute respiratory syndrome-coronavirus 2 (SARS-Cov-2) has led to over 13 million cases of coronavirus disease (COVID-19) with a significant mortality rate. laboratory rat has been a supporter of the development of therapies and vaccines; However, they do not support infection by SARS-CoV virus-2 because of the inability to use the mouse orthologue inclusion of human angiotensin-converting enzyme receptor 2 (hACE2). While hACE2 support infection and pathogenesis of transgenic mice, these mice were limited in availability and are limited to a single genetic background.

Here we report the development of a mouse model of SARS-CoV-2 is based on adeno-associated virus (AAV) -mediated expression of hACE2. These mice support replication of the virus and showed pathological findings were found in 19 patients COVID. In addition, we show that type I interferon does not control the SARS-CoV-2 replication in vivo but is a significant driver of pathological response. Thus, AAV-hACE2 rat models enables rapid deployment for a strong following in-depth analysis of SARS-CoV infection-2 with patient derived virus is authentic in mice genetically diverse backgrounds.

Mouse-to-Mouse Blocking Reagent

MTM125 125 ml
EUR 362

Mouse-to-Mouse Blocking Reagent

MTM500 500 ml
EUR 826

Mouse Anti Mouse Cd44 Monoclonal Antibody

CABT-46107MM 0.25 mg
EUR 663

Mouse to Mouse HRP Staining System

MTM003 400 Slides
EUR 361

Mouse, CD14 Mouse Recombinant Protein, Sf9

PROTP10810-1 Regular: 10ug
EUR 317
Description: CD14 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 357 amino acids (16-366a.a.) and having a molecular mass of 38.3kDa. _x000D_ (Molecular size on SDS-PAGE will appear at approximately 40-57kDa)._x000D_ CD14 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

Mouse, GAPDH Mouse Recombinant Protein, Active

PROTP16858-1 Regular: 10ug
EUR 317
Description: GAPDH Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 356 amino acids (1-333a.a.) and having a molecular mass of 38.2kDa.;GAPDH is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Mouse, Bax Mouse Recombinant Protein, GST

PROTQ07813-1 Regular: 10ug
EUR 317
Description: Bax Mouse Recombinant amino acid 1-171 produced in E.Coli is a single, non-glycosylated polypeptide chain. ;The Mouse Bax is purified by proprietary chromatographic techniques.

Parstatin (mouse)

B5451-1 1 mg
EUR 772

Mouse IgG1

C040307-10mg 10mg
EUR 1790

Mouse IgG1

C040307-1mg 1mg
EUR 607

Mouse IgG2a

C040308-10mg 10mg
EUR 1790

Mouse IgG2a

C040308-1mg 1mg
EUR 607

Mouse IgG2b

C040309-10mg 10mg
EUR 1790

Mouse IgG2b

C040309-1mg 1mg
EUR 607

Mouse IgG3

C040310-10mg 10mg
EUR 1790

Mouse IgG3

C040310-1mg 1mg
EUR 607

Mouse IgM

C040311-10mg 10mg
EUR 1790

Mouse IgM

C040311-1mg 1mg
EUR 607

Mouse IgA

C040312-10mg 10mg
EUR 1790

Mouse IgA

C040312-1mg 1mg
EUR 607

Mouse IgG

E61I007 1mg
EUR 343

CRAMP (mouse)

H-6526.0001 1.0mg
EUR 273
Description: Sum Formula: C178H302N50O46; CAS# [376364-36-2] net

CRAMP (mouse)

H-6526.0005 5.0mg
EUR 998
Description: Sum Formula: C178H302N50O46; CAS# [376364-36-2] net

Endotrophin (mouse)

H-7382.0100 0.1mg
EUR 383
Description: Sum Formula: C345H520N92O106S7; CAS# [1678414-54-4] net

Endotrophin (mouse)

H-7382.0500 0.5mg
EUR 1438
Description: Sum Formula: C345H520N92O106S7; CAS# [1678414-54-4] net

ADAM10 (Mouse)

GT15079 100 ug
EUR 526

EGF, Mouse

HY-P7067 100ug
EUR 187

LIF, Mouse

HY-P7084 50ug
EUR 533

Adiponectin, Mouse

HY-P7129 50ug
EUR 418

CCL6, Mouse

HY-P7143 10ug
EUR 268

CNTF, Mouse

HY-P7147 10ug
EUR 211

CXCL16, Mouse

HY-P7151 10ug
EUR 268

CXCL3, Mouse

HY-P7153 50ug
EUR 670

OSM, Mouse

HY-P7275 50ug
EUR 762

Shh, Mouse

HY-P7290 50ug
EUR 567

VEGF165, Mouse

HY-P7312 50ug
EUR 807

Betacellulin, Mouse

HY-P7329 50ug
EUR 612

DHH, Mouse

HY-P7339 50ug
EUR 497

MIF, Mouse

HY-P7388 10ug
EUR 234

Mouse HSV

EMH0317 96Tests
EUR 521

Mouse HSV

EMH0318 96Tests
EUR 521

Mouse Serum

abx098261-100L 100 L
EUR 129506
  • Shipped within 5-10 working days.

Mouse Serum

20-abx098261
  • EUR 1163.00
  • EUR 272.00
  • 100 ml
  • 10 ml
  • Shipped within 5-10 working days.

Mouse Serum

abx098261-5L 5 L
EUR 8833
  • Shipped within 5-10 working days.

Mouse Serum

abx098262-1ml 1 ml
EUR 1720
  • Shipped within 5-10 working days.

GHRF, mouse

5-01202 0.4 x 5mg Ask for price

mCRAMP, mouse

5-01528 4 x 1mg Ask for price

Mouse IgG

1265-100
EUR 153

Mouse IgG

1265-1000
EUR 370

Mouse ; Thymocyte

02-703 100ng
EUR 401
Description: The Mouse ; Thymocyte is available in Europe and for worldwide shipping via Gentaur.

Mouse ; Testis

02-715 100ng
EUR 401
Description: The Mouse ; Testis is available in Europe and for worldwide shipping via Gentaur.

Mouse IgG

31-AM15 10 mg
EUR 215
Description: Purified Mouse IgG

Mouse IgG

31-AM15S 10 mg
EUR 130
Description: Purified Mouse IgG

Mouse IgG1

31C-CH1004 1 mg
EUR 377
Description: Purified Mouse IgG1

Mouse IgG2a

31C-CH1007 1 mg
EUR 377
Description: Purified Mouse IgG2a

Mouse IgG2b

31C-CH1010 1 mg
EUR 365
Description: Purified Mouse IgG2b

Mouse IgG3

31C-CH1013 1 mg
EUR 365
Description: Purified Mouse IgG3

Mouse IgM

31C-CH1025 1 mg
EUR 365
Description: Purified Mouse IgM

Mouse Cardiomyocytes

PC35136 P0 Mouse - Whole Heart Dissociated Cells X2
EUR 1419

Leptin-Mouse

PR27099 200 ug
EUR 191

LIF, mouse

MO16102 100 ug
EUR 675

mCherry - Mouse

MO22140 100 ul
EUR 435

ExoStep Mouse

MOExoS-25-C9 25 test
EUR 537.5

EGF Mouse

P2558-.1 100 µg
EUR 108

EGF Mouse

P2558-.5 500 µg
EUR 200

EGF Mouse

P2558-1 1 mg
EUR 311

mCRAMP, mouse

SP-88328-1 1 mg
EUR 286

Mouse Monoclonal Anti-Mouse CD11a, Biotin (Clone 8-6.2) (mouse IgG2a)

MCD011A-B 100 tests
EUR 469

Mouse Monoclonal Anti-Mouse CD11a, FITC (Clone 8-6.2) (mouse IgG2a)

MCD011A-F 100 tests
EUR 469

Mouse Monoclonal Anti-Mouse CD11a, Purified (Clone 8-6.2) (mouse IgG2a)

MCD011A-M 100 ug
EUR 482

Mouse Monoclonal Anti-Mouse CD11a, PE (Clone 8-6.2) (mouse IgG2a)

MCD011A-PE 100 tests
EUR 469

Mouse Monoclonal Anti-Mouse CD72.1, Biotin (Clone CT-72.1) (mouse IgG2a)

MCD072-B 100 tests
EUR 469

Mouse Monoclonal Anti-Mouse CD72.1, FITC (Clone CT-72.1) (mouse IgG2a)

MCD072-F 100 tests
EUR 469

Mouse Monoclonal Anti-Mouse CD72.1, Purified (Clone CT-72.1) (mouse IgG2a)

MCD072-M 100 ug
EUR 482

Mouse Monoclonal Anti-Mouse CD72.1, PE (Clone CT-72.1) (mouse IgG2a)

MCD072-PE 100 tests
EUR 469

Mouse Monoclonal Anti-Mouse/Rat CD81, Biotin (Clone Eat2)(mouse IgG1)

MCD081-B 100 tests
EUR 469

Mouse Monoclonal Anti-Mouse/Rat CD81, FITC (Clone Eat2)(mouse IgG1)

MCD081-F 100 tests
EUR 469

Mouse Monoclonal Anti-Mouse/Rat CD81, PE (Clone Eat2)(mouse IgG1)

MCD081-PE 100 tests
EUR 469

Mouse Monoclonal Anti-Mouse/Rat CD81, Purified (Clone Eat2)(mouse IgG1)

MCD081-UL 100 ug
EUR 347

Mouse Anti Mouse Cd14 Monoclonal Antibody,RPE

CABT-45608MM 100 TEST
EUR 533

Mouse Anti Mouse Cd44 Monoclonal Antibody,RPE

CABT-46109MM 100 TEST
EUR 533

Mouse Anti Mouse Cd28 Monoclonal Antibody,RPE

CABT-48085MM 100 TEST
EUR 533

Mouse APT(Mouse Abnormal prothrombin) ELISA Kit

EM1857 96T
EUR 567.6
  • Detection range: 0.156-10 ng/ml
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml

Mouse Anti Mouse Nc1.1 Monoclonal Antibody,RPE

DMABT-54461MM 25 TEST
EUR 429

Mouse Monoclonal Anti-Mouse Myeloperoxidase (MPO) IgG

MPO12-M 100 ul
EUR 482

Mouse to Mouse HRP (DAB) Staining System

MTM001 70 Slides
EUR 157

Mouse to Mouse HRP (AEC) Staining System

MTM002 70 Slides
EUR 157

Mouse to Mouse Alk-Phos Staining System

MTM005 400 Slides
EUR 361

Mouse monoclonal Anti-rat/mouse lactoferrin IgG

LTF15-M 100 ul
EUR 482

Mouse, Flt3 Ligand Mouse Recombinant Protein, Sf9

PROTP49772-1 Regular: 5ug
EUR 317
Description: Flt3 Ligand produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain (27-189 a.a.) and fused to a 6 aa His Tag at C-terminus containing a total of 169 amino acids and having a molecular mass of 19.3kDa.;Flt3 Ligand shows multiple bands between 18-28kDa on SDS-PAGE, reducing conditions and purified by proprietary chromatographic techniques.

Acrp30 Mouse, Adiponectin Mouse Recombinant Protein, HEK

PROTQ60994-2 Regular: 10ug
EUR 317
Description: The Acrp30 Mouse Recombinant is fused with FLAG tag having a total Mw of 26kDa.

Mouse, Resistin Mouse Recombinant Protein, His Tag

PROTQ99P87 Regular: 25ug
EUR 317
Description: Resistin Mouse is manufactured with signal sequence of phage fd (21aa) and C-terminal fusion of flagTag (10aa). Resistin Mouse Recombinant Flag-Tagged Fusion Protein is 13.7 kDa protein containing 93 amino acid residues of the Resistin Mouse and 31 additional amino acid residues - signal sequence of phage fd, flagTag (underlined).

Mouse Monoclonal Anti-Mouse CD5 (Ly 1.2), Biotin (Clone CG16) (mouse IgG2b)

MCD005-B 100 tests
EUR 469

Mouse Monoclonal Anti-Mouse CD5 (Ly 1.2), FITC (Clone CG16) (mouse IgG2b)

MCD005-F 100 tests
EUR 469

Mouse Monoclonal Anti-Mouse CD5 (Ly 1.2), PE (Clone CG16) (mouse IgG2b)

MCD005-PE 100 tests
EUR 469

Mouse Monoclonal Anti-Mouse CD160 mAb, Biotin, (clone CNX46-3), (mouse IgG2bk)

MCD160-B 100 tests
EUR 469

Mouse Monoclonal Anti-Mouse CD160 mAb, FITC, (clone CNX46-3), (mouse IgG2bk)

MCD160-F 50 Tests
EUR 408

Mouse Monoclonal Anti-Mouse CD160 mAb, Purified, (clone CNX46-3), (mouse IgG2bk)

MCD160-M 100 ug
EUR 482

Mouse Monoclonal Anti-Mouse CD160 mAb, PE, (clone CNX46-3), (mouse IgG2bk)

MCD160-PE 50 tests
EUR 347

Mouse Monoclonal Anti-Mouse CD5 (Ly 1.2), No Azide (Clone CG16) (mouse IgG2b)

MCD005-M 100 Tests
EUR 482

Mouse Anti-Mouse TIGIT Monoclonal antibody, clone 1G9

CABT-L4298-1mg 1 mg
EUR 897

Mouse Anti-Mouse TIGIT Monoclonal antibody, clone 1G9

CABT-L4298-5mg 5 mg
EUR 2405

Mouse Anti-Mouse CD22 Monoclonal antibody, clone Cy34.1

CABT-L4309-1mg 1 mg
EUR 897

Mouse Anti-Mouse CD22 Monoclonal antibody, clone Cy34.1

CABT-L4309-5mg 5 mg
EUR 2405

Mouse Anti-Mouse NK1.1 Monoclonal antibody, clone PK136

CABT-L4348-1mg 1 mg
EUR 897

Mouse Anti-Mouse NK1.1 Monoclonal antibody, clone PK136

CABT-L4348-5mg 5 mg
EUR 2405

Mouse Anti-Mouse CD45.2 Monoclonal antibody, clone 104.2

CABT-L4528-1mg 1 mg
EUR 897

Mouse Anti-Mouse CD45.2 Monoclonal antibody, clone 104.2

CABT-L4528-5mg 5 mg
EUR 2405

Mouse Anti Mouse Cd28 Monoclonal Antibody,Low Endotoxin

CABT-48083MM 0.5 mg
EUR 881

Mouse IgG1 (FITC) / Mouse IgG1 (RPE) Isotype Control

abx405001-50tests 50 tests
EUR 634
  • Shipped within 1 week.

Mouse IgG2a (FITC) / Mouse IgG2a (RPE) Isotype Control

abx405002-50tests 50 tests
EUR 620
  • Shipped within 1 week.

Mouse IgG1 (FITC) / Mouse IgG2a (RPE) Isotype Control

abx405003-50tests 50 tests
EUR 620
  • Shipped within 1 week.

Mouse IgG1 (FITC) / Mouse IgG1 (RPE) Isotype Control

abx405005-100tests 100 tests
EUR 620
  • Shipped within 1 week.

Pancreas Dissociation System 5 (Acinar, mouse parotid), Mouse

4-20375 ea Ask for price

Mouse Anti Mouse Nc1.1 Monoclonal Antibody,Azide Free

DMABT-54458MM 1 mg
EUR 1261

IL3 Mouse, Interleukin-3 Mouse Recombinant Protein, sf9

PROTP01586-1 Regular: 5ug
EUR 317
Description: IL3 Mouse Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 148 amino acids (27-166 a.a.) and having a molecular mass of 16.7kDa (Migrates at 18-28kDa on SDS-PAGE under reducing conditions).;IL3 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

CTSB Mouse, Cathepsin-B Mouse Recombinant Protein, Active

PROTP10605-1 Regular: 10ug
EUR 317
Description: CTSB Mouse Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 330 amino acids (18-339a.a.) and having a molecular mass of 36.4kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa)._x000D_ CTSB is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

CST3 Mouse, Cystatin-C Mouse Recombinant Protein, sf9

PROTP21460-2 Regular: 10ug
EUR 317
Description: CST3 produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 126 amino acids (21-140a.a.) and having a molecular mass of 14.2kDa. (Molecular size on SDS-PAGE will appear at approximately 13.5-18kDa).;CST3 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

CST3 Mouse, Cystatin-C, Recombinant Protein Mouse Active

PROTP21460-3 Regular: 10ug
EUR 317
Description: CST3 Mouse produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 126 amino acids (21-140 a.a.) and having a molecular mass of 14.2kDa (Molecular size on SDS-PAGE will appear at approximately 13.5-18kDa).;CST3 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

CST3 Mouse, Cystatin-C Mouse Recombinant Protein, Active

PROTP21460-4 Regular: 10ug
EUR 317
Description: CST3 Mouse produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 126 amino acids (21-140 a.a.) and having a molecular mass of 14.2kDa (Molecular size on SDS-PAGE will appear at approximately 13.5-18kDa).;CST3 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

Acrp30 Mouse, Adiponectin Mouse Recombinant Protein, Trimeric form

PROTQ60994 Regular: 10ug
EUR 317
Description: Trimeric form of Acrp30 Mouse was expressed in HEK293 cells.;The cysteine 39 was replaced with alanine (C39A) 9. mAd-C39A can only form trimer, but not hexamer or HMW form.

Acrp30 Mouse, Adiponectin Mouse Recombinant Protein, His Tag

PROTQ60994-3 Regular: 25ug
EUR 317
Description: The Adiponectin Mouse is created as a recombinant protein with a 21 a.a N-terminal fusion of His Tag. The Adiponectin His-Tagged Fusion Protein, produced in E. coli, is a 27.2kDa protein containing 251 amino acid residues of the Acrp30 Mouse, 18-247 amino acids.

Recombinant Mouse Endoglin

CC028-002 2ug
EUR 293

Recombinant Mouse Endoglin

CC028-010 10ug
EUR 408

Recombinant Mouse Endoglin

CC028-100 100ug
EUR 3155

Recombinant Mouse Resistin

CC127-005 5ug
EUR 293

Recombinant Mouse Resistin

CC127-025 25ug
EUR 408

Recombinant Mouse Resistin

CC127-101 1mg
EUR 10310

Mouse ZFHX1B Protein

20-abx650842
  • EUR 857.00
  • EUR 314.00
  • EUR 2750.00
  • EUR 1024.00
  • EUR 592.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse NCOA6 Protein

20-abx650854
  • EUR 620.00
  • EUR 272.00
  • EUR 1859.00
  • EUR 732.00
  • EUR 453.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse SYMPK Protein

20-abx650872
  • EUR 676.00
  • EUR 272.00
  • EUR 2054.00
  • EUR 801.00
  • EUR 481.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse AVPI1 Protein

20-abx650886
  • EUR 620.00
  • EUR 272.00
  • EUR 1859.00
  • EUR 732.00
  • EUR 453.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse TCEA3 Protein

20-abx650888
  • EUR 746.00
  • EUR 286.00
  • EUR 2318.00
  • EUR 885.00
  • EUR 523.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse PEX19 Protein

20-abx650905
  • EUR 537.00
  • EUR 244.00
  • EUR 1553.00
  • EUR 634.00
  • EUR 398.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse TRIM5 Protein

20-abx650912
  • EUR 620.00
  • EUR 272.00
  • EUR 1859.00
  • EUR 732.00
  • EUR 453.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse TIF1b Protein

20-abx650914
  • EUR 439.00
  • EUR 230.00
  • EUR 1191.00
  • EUR 509.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse NCOR1 Protein

20-abx650928
  • EUR 620.00
  • EUR 272.00
  • EUR 1859.00
  • EUR 732.00
  • EUR 453.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse XYLT1 Protein

20-abx650933
  • EUR 857.00
  • EUR 314.00
  • EUR 2750.00
  • EUR 1024.00
  • EUR 592.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse CASC1 Protein

20-abx650947
  • EUR 620.00
  • EUR 272.00
  • EUR 1859.00
  • EUR 732.00
  • EUR 453.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse CASC5 Protein

20-abx650949
  • EUR 620.00
  • EUR 272.00
  • EUR 1859.00
  • EUR 732.00
  • EUR 453.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse FLRT1 Protein

20-abx650960
  • EUR 523.00
  • EUR 244.00
  • EUR 1497.00
  • EUR 606.00
  • EUR 384.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse GRB14 Protein

20-abx650968
  • EUR 592.00
  • EUR 258.00
  • EUR 1776.00
  • EUR 704.00
  • EUR 439.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse CASQ Protein

20-abx650977
  • EUR 620.00
  • EUR 272.00
  • EUR 1859.00
  • EUR 732.00
  • EUR 453.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse CASQ2 Protein

20-abx650978
  • EUR 537.00
  • EUR 244.00
  • EUR 1553.00
  • EUR 634.00
  • EUR 398.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse IHPK3 Protein

20-abx650982
  • EUR 537.00
  • EUR 244.00
  • EUR 1553.00
  • EUR 634.00
  • EUR 398.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse IFNb Protein

20-abx650985
  • EUR 801.00
  • EUR 300.00
  • EUR 2527.00
  • EUR 954.00
  • EUR 565.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse DKK1 Protein

20-abx650986
  • EUR 690.00
  • EUR 286.00
  • EUR 2124.00
  • EUR 815.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse VIM Protein

20-abx650987
  • EUR 704.00
  • EUR 286.00
  • EUR 2165.00
  • EUR 829.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse AD Protein

20-abx650992
  • EUR 787.00
  • EUR 300.00
  • EUR 2486.00
  • EUR 940.00
  • EUR 551.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse VTN Protein

20-abx651001
  • EUR 704.00
  • EUR 286.00
  • EUR 2165.00
  • EUR 829.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse OPN Protein

20-abx651006
  • EUR 662.00
  • EUR 272.00
  • EUR 2040.00
  • EUR 787.00
  • EUR 481.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Orexin B (mouse)

B5119-.5 500 ?g
EUR 337

Orexin B (mouse)

B5119-1 1 mg
EUR 487

Orexin B (mouse)

B5119-5 5 mg
EUR 1784

Orexin B (mouse)

B5119-5.1 10 mM (in 1mL DMSO)
EUR 11252

Hemokinin 1 (mouse)

B5127-1 1 mg
EUR 321

Hemokinin 1 (mouse)

B5127-10 10 mg
EUR 1407

Hemokinin 1 (mouse)

B5127-5 5 mg
EUR 864

Hemopressin (human, mouse)

B5476-1 1 mg
EUR 318

anti-mouse VLK

AR03-PA0002 100 ul
EUR 334
Description: Rabbit polyclonal to VLK

mouse Splunc2 Antibody

BF0461 200ul
EUR 376
Description: mouse Splunc2 antibody detects endogenous levels of total mouse Splunc2.

CLDN6 Mouse mAb

BF8001 100ul
EUR 304
Description: Affinity-chromatography.

Fibronectin Mouse mAb

BF9010 200ul
EUR 376
Description: The Fibronectin antibody can recognize endogenous Fibronectin proteins.

eIF4A1 Mouse mAb

BF9011 100 ug
EUR 438

HSP70 Mouse mAb

BF9012 200ul
EUR 376
Description: The HSP70 mouse monoclonal antibody can detect endogenous HSP70 proteins.

CK7 Mouse mAb

BF9202 100 ug
EUR 438

XRCC4 Mouse mAb

BF9204 100 ug
EUR 438

Oct1 Mouse mAb

BF9205 100 ug
EUR 438

CD16 Mouse mAb

BF9207 100 ug
EUR 438

PCNA Mouse mAb

BF9209 100 ug
EUR 438

MAP2 Mouse mAb

BF9214 100 ug
EUR 438

GFAP Mouse mAb

BF9215 100 ug
EUR 438

Transferrin Mouse mAb

BF9216 100 ug
EUR 438

eNOS Mouse mAb

BF9300 100 ug
EUR 438

P65 Mouse mAb

BF9302 100 ug
EUR 438

cox2 Mouse mAb

BF9303 100 ug
EUR 438

p53 Mouse mAb

BF9304 100 ug
EUR 438

NSE Mouse mAb

BF9305 100 ug
EUR 438

Mouse IGFBP-5

BP5DU010 10 µg
EUR 253

Ghrelin (mouse, rat)

H-4862.0500 0.5mg
EUR 515
Description: Sum Formula: C147H245N45O42; CAS# [258338-12-4] net

Ghrelin (mouse, rat)

H-4862.1000 1.0mg
EUR 877
Description: Sum Formula: C147H245N45O42; CAS# [258338-12-4] net

Secretoneurin (mouse, rat)

H-5512.0500 0.5mg
EUR 347
Description: Sum Formula: C159H252N40O58; CAS# [149146-12-3] net

rec Leptin (mouse)

H-5582.0200 0.2mg
EUR 162
Description: CAS# [1061787-61-8]

rec Leptin (mouse)

H-5582.1000 1.0mg
EUR 381
Description: CAS# [1061787-61-8]

Urocortin III (mouse)

H-5828.0500 0.5mg
EUR 410
Description: Sum Formula: C186H312N52O52S2; CAS# [357952-10-4] net

Urocortin III (mouse)

H-5828.1000 1.0mg
EUR 708
Description: Sum Formula: C186H312N52O52S2; CAS# [357952-10-4] net

Urocortin II (mouse)

H-6238.0500 0.5mg
EUR 515
Description: Sum Formula: C187H320N56O50; CAS# [330648-32-3] net

Urocortin II (mouse)

H-6238.1000 1.0mg
EUR 803
Description: Sum Formula: C187H320N56O50; CAS# [330648-32-3] net

Nesfatin-1 (mouse)

H-6474.0050 50.0µg
EUR 515
Description: Sum Formula: C424H683N117O137; CAS# [917528-36-0] net

Nesfatin-1 (mouse)

H-6474.0250 250.0µg
EUR 1965
Description: Sum Formula: C424H683N117O137; CAS# [917528-36-0] net


Toxoplasma encephalitis is an AIDS-defining condition. The decline in CD4 + T cell IFN-γ-producing AIDS is a major factor in silent reactivation of Toxoplasma gondii to replicate the active stage of infection. Therefore, it is important to characterize the CD4-independent mechanisms that limit acute T. gondii infection. We investigated the in vivo regulation of IFN-γ production by CD8 + T cells, DN T cells and NK cells in response to acute T. gondii infection.

Our data suggest that IFN-γ treatment by non-CD4 cells is dependent on both IL-12 and IL-18, and secretion of bioactive IL-18 in response to T. gondii parasite requires sensing inflammasome feasible by multiple redundant sensors in several hematopoietic cell types.

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