Interferon-α2b spray inhalation did not shorten virus shedding time of SARS-CoV-2 in hospitalized patients: a preliminary matched case-control study

Interferon-α2b spray inhalation did not shorten virus shedding time of SARS-CoV-2 in hospitalized patients: a preliminary matched case-control study

Background: Interferon regulatory factor 6 functions (IRF6) exhibits tumor-suppression in multiple types of cancer. Here, the antitumor properties and pathways involved in the mechanism of IRF6 investigated in cervical cancer.


Methods: Forty-one pairs of cervical cancer specimens and para-carcinoma tissues were collected to evaluate IRF6 expression using immunohistochemical (IHC) staining and miR-587. Effects of miR-587 and IRF6 in the growth of cervical cancer cells explored by MTT test and HeLa tumor mouse xenograft model. Migration and invasion of cervical cancer cells are monitored using transwell test.


Results: Expression of IRF6 in cervical cancer specimens and cell lines were significantly reduced compared with a suitable control group. In addition, the IRF6 expression negatively correlated with miR-587 in cervical cancer tissue. Bioinformatics algorithms and luciferase tests revealed that IRF6 is a potential target of miR-587 and miR-587 mimic transfection cause significant suppression of the IRF6 protein levels in cervical cancer cells. We also found that the antineoplastic properties of IRF6 can be reversed by overexpressing miR-587 in cervical cancer cells. Upregulation of miR-587 correlated with poor overall survival in cervical cancer. In an experiment in vivo silencing of miR-587 induced tumor growth inhibition HeLa, which was associated with upregulation of IRF6 protein in the tumor.


Conclusion: miR-587 represses posttranscriptionally IRF6 protein expression to cancel the antineoplastic activity of IRF6. The miR-587 / IRF6 signaling pathway plays an important role in the development of cervical cancer and serve as a potential therapeutic target for the treatment of cervical cancer.

 Interferon-α2b spray inhalation did not shorten virus shedding time of SARS-CoV-2 in hospitalized patients: a preliminary matched case-control study
Interferon-α2b spray inhalation did not shorten virus shedding time of SARS-CoV-2 in hospitalized patients: a preliminary matched case-control study

a mouse model of SARS-CoV-2 expressing inflammatory role of type I interferon signaling

acute respiratory syndrome-coronavirus 2 (SARS-Cov-2) has led to over 13 million cases of coronavirus disease (COVID-19) with a significant mortality rate. laboratory rat has been a supporter of the development of therapies and vaccines; However, they do not support infection by SARS-CoV virus-2 because of the inability to use the mouse orthologue inclusion of human angiotensin-converting enzyme receptor 2 (hACE2). While hACE2 support infection and pathogenesis of transgenic mice, these mice were limited in availability and are limited to a single genetic background.

Here we report the development of a mouse model of SARS-CoV-2 is based on adeno-associated virus (AAV) -mediated expression of hACE2. These mice support replication of the virus and showed pathological findings were found in 19 patients COVID. In addition, we show that type I interferon does not control the SARS-CoV-2 replication in vivo but is a significant driver of pathological response. Thus, AAV-hACE2 rat models enables rapid deployment for a strong following in-depth analysis of SARS-CoV infection-2 with patient derived virus is authentic in mice genetically diverse backgrounds.

Mouse-to-Mouse Blocking Reagent

MTM008 8 ml
EUR 96

Mouse-to-Mouse Blocking Reagent

MTM015 15 ml
EUR 105.6

Mouse-to-Mouse Blocking Reagent

MTM125 125 ml
EUR 434.4

Mouse-to-Mouse Blocking Reagent

MTM500 500 ml
EUR 991.2

Mouse Anti Mouse Cd44 Monoclonal Antibody

CABT-46107MM 0.25 mg
EUR 795.6

Mouse to Mouse HRP Staining System

MTM003 400 Slides
EUR 433.2

Mouse, CD14 Mouse Recombinant Protein, Sf9

PROTP10810-1 Regular: 10ug
EUR 380.4
Description: CD14 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 357 amino acids (16-366a.a.) and having a molecular mass of 38.3kDa. _x000D_ (Molecular size on SDS-PAGE will appear at approximately 40-57kDa)._x000D_ CD14 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

Mouse, GAPDH Mouse Recombinant Protein, Active

PROTP16858-1 Regular: 10ug
EUR 380.4
Description: GAPDH Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 356 amino acids (1-333a.a.) and having a molecular mass of 38.2kDa.;GAPDH is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Mouse, Bax Mouse Recombinant Protein, GST

PROTQ07813-1 Regular: 10ug
EUR 380.4
Description: Bax Mouse Recombinant amino acid 1-171 produced in E.Coli is a single, non-glycosylated polypeptide chain. ;The Mouse Bax is purified by proprietary chromatographic techniques.

Mouse IgG1

31C-CH1004 1 mg
EUR 452.4
Description: Purified Mouse IgG1

Mouse IgG2a

31C-CH1007 1 mg
EUR 452.4
Description: Purified Mouse IgG2a

Mouse IgG2b

31C-CH1010 1 mg
EUR 438
Description: Purified Mouse IgG2b

Mouse IgG3

31C-CH1013 1 mg
EUR 438
Description: Purified Mouse IgG3

Mouse IgM

31C-CH1025 1 mg
EUR 438
Description: Purified Mouse IgM

GHRF, mouse

5-01202 0.4 x 5mg Ask for price

mCRAMP, mouse

5-01528 4 x 1mg Ask for price

Mouse IgG

1265-100
EUR 183.6

Mouse IgG

1265-1000
EUR 444

Mouse IgG

31-AM15 10 mg
EUR 258
Description: Purified Mouse IgG

Mouse IgG

31-AM15S 10 mg
EUR 156
Description: Purified Mouse IgG

Mouse ; Thymocyte

02-703 100ng
EUR 481.2
Description: The Mouse ; Thymocyte is available in Europe and for worldwide shipping via Gentaur.

Mouse ; Testis

02-715 100ng
EUR 481.2
Description: The Mouse ; Testis is available in Europe and for worldwide shipping via Gentaur.

Mouse Serum

abx098261-100L 100 L
EUR 155407.2

Mouse Serum

20-abx098261
  • EUR 1395.60
  • EUR 326.40
  • 100 ml
  • 10 ml

Mouse Serum

abx098261-5L 5 L
EUR 10599.6

Mouse Serum

abx098262-1ml 1 ml
EUR 2064

Parstatin (mouse)

B5451-1 1 mg
EUR 926.4

Mouse IgG1

C040307-10mg 10mg
EUR 2148

Mouse IgG1

C040307-1mg 1mg
EUR 728.4

Mouse IgG2a

C040308-10mg 10mg
EUR 2148

Mouse IgG2a

C040308-1mg 1mg
EUR 728.4

Mouse IgG2b

C040309-10mg 10mg
EUR 2148

Mouse IgG2b

C040309-1mg 1mg
EUR 728.4

Mouse IgG3

C040310-10mg 10mg
EUR 2148

Mouse IgG3

C040310-1mg 1mg
EUR 728.4

Mouse IgM

C040311-10mg 10mg
EUR 2148

Mouse IgM

C040311-1mg 1mg
EUR 728.4

Mouse IgA

C040312-10mg 10mg
EUR 2148

Mouse IgA

C040312-1mg 1mg
EUR 728.4

Mouse HSV

EMH0317 96Tests
EUR 625.2

Mouse HSV

EMH0318 96Tests
EUR 625.2

LIF, mouse

MO16102 100 ug
EUR 810

mCherry - Mouse

MO22140 100 ul
EUR 522

ExoStep Mouse

MOExoS-25-C9 25 test
EUR 645

Mouse IgG

E61I007 1mg
EUR 411.6

EGF, Mouse

HY-P7067 100ug
EUR 224.4

LIF, Mouse

HY-P7084 50ug
EUR 639.6

Adiponectin, Mouse

HY-P7129 50ug
EUR 501.6

CCL6, Mouse

HY-P7143 10ug
EUR 321.6

CNTF, Mouse

HY-P7147 10ug
EUR 253.2

CXCL16, Mouse

HY-P7151 10ug
EUR 321.6

CXCL3, Mouse

HY-P7153 50ug
EUR 804

OSM, Mouse

HY-P7275 50ug
EUR 914.4

Shh, Mouse

HY-P7290 50ug
EUR 680.4

VEGF165, Mouse

HY-P7312 50ug
EUR 968.4

Betacellulin, Mouse

HY-P7329 50ug
EUR 734.4

DHH, Mouse

HY-P7339 50ug
EUR 596.4

MIF, Mouse

HY-P7388 10ug
EUR 280.8

CRAMP (mouse)

H-6526.0001 1.0mg
EUR 327.6
Description: Sum Formula: C178H302N50O46; CAS# [376364-36-2] net

CRAMP (mouse)

H-6526.0005 5.0mg
EUR 1197.6
Description: Sum Formula: C178H302N50O46; CAS# [376364-36-2] net

Endotrophin (mouse)

H-7382.0100 0.1mg
EUR 459.6
Description: Sum Formula: C345H520N92O106S7; CAS# [1678414-54-4] net

Endotrophin (mouse)

H-7382.0500 0.5mg
EUR 1725.6
Description: Sum Formula: C345H520N92O106S7; CAS# [1678414-54-4] net

ADAM10 (Mouse)

GT15079 100 ug
EUR 631.2

EGF Mouse

P2558-.1 100 µg
EUR 129.6

EGF Mouse

P2558-.5 500 µg
EUR 240

EGF Mouse

P2558-1 1 mg
EUR 373.2

Leptin-Mouse

PR27099 200 ug
EUR 229.2

Mouse Cardiomyocytes

PC35136 P0 Mouse - Whole Heart Dissociated Cells X2
EUR 1702.8

mCRAMP, mouse

SP-88328-1 1 mg
EUR 343.2

Mouse Ig

RPN10012ML EACH
EUR 429.78

Mouse Monoclonal Anti-Mouse CD11a, Biotin (Clone 8-6.2) (mouse IgG2a)

MCD011A-B 100 tests
EUR 562.8

Mouse Monoclonal Anti-Mouse CD11a, FITC (Clone 8-6.2) (mouse IgG2a)

MCD011A-F 100 tests
EUR 562.8

Mouse Monoclonal Anti-Mouse CD11a, Purified (Clone 8-6.2) (mouse IgG2a)

MCD011A-M 100 ug
EUR 578.4

Mouse Monoclonal Anti-Mouse CD11a, PE (Clone 8-6.2) (mouse IgG2a)

MCD011A-PE 100 tests
EUR 562.8

Mouse Monoclonal Anti-Mouse CD72.1, Biotin (Clone CT-72.1) (mouse IgG2a)

MCD072-B 100 tests
EUR 562.8

Mouse Monoclonal Anti-Mouse CD72.1, FITC (Clone CT-72.1) (mouse IgG2a)

MCD072-F 100 tests
EUR 562.8

Mouse Monoclonal Anti-Mouse CD72.1, Purified (Clone CT-72.1) (mouse IgG2a)

MCD072-M 100 ug
EUR 578.4

Mouse Monoclonal Anti-Mouse CD72.1, PE (Clone CT-72.1) (mouse IgG2a)

MCD072-PE 100 tests
EUR 562.8

Mouse Monoclonal Anti-Mouse/Rat CD81, Biotin (Clone Eat2)(mouse IgG1)

MCD081-B 100 tests
EUR 562.8

Mouse Monoclonal Anti-Mouse/Rat CD81, FITC (Clone Eat2)(mouse IgG1)

MCD081-F 100 tests
EUR 562.8

Mouse Monoclonal Anti-Mouse/Rat CD81, PE (Clone Eat2)(mouse IgG1)

MCD081-PE 100 tests
EUR 562.8

Mouse Monoclonal Anti-Mouse/Rat CD81, Purified (Clone Eat2)(mouse IgG1)

MCD081-UL 100 ug
EUR 416.4

Mouse Anti Mouse Cd14 Monoclonal Antibody,RPE

CABT-45608MM 100 TEST
EUR 639.6

Mouse Anti Mouse Cd44 Monoclonal Antibody,RPE

CABT-46109MM 100 TEST
EUR 639.6

Mouse Anti Mouse Cd28 Monoclonal Antibody,RPE

CABT-48085MM 100 TEST
EUR 639.6

Mouse Anti Mouse Nc1.1 Monoclonal Antibody,RPE

DMABT-54461MM 25 TEST
EUR 514.8

Mouse APT(Mouse Abnormal prothrombin) ELISA Kit

EM1857 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml

Mouse Monoclonal Anti-Mouse Myeloperoxidase (MPO) IgG

MPO12-M 100 ul
EUR 578.4

Mouse to Mouse HRP (DAB) Staining System

MTM001 70 Slides
EUR 188.4

Mouse to Mouse HRP (AEC) Staining System

MTM002 70 Slides
EUR 188.4

Mouse to Mouse Alk-Phos Staining System

MTM005 400 Slides
EUR 433.2

Mouse monoclonal Anti-rat/mouse lactoferrin IgG

LTF15-M 100 ul
EUR 578.4

Mouse, Flt3 Ligand Mouse Recombinant Protein, Sf9

PROTP49772-1 Regular: 5ug
EUR 380.4
Description: Flt3 Ligand produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain (27-189 a.a.) and fused to a 6 aa His Tag at C-terminus containing a total of 169 amino acids and having a molecular mass of 19.3kDa.;Flt3 Ligand shows multiple bands between 18-28kDa on SDS-PAGE, reducing conditions and purified by proprietary chromatographic techniques.

Acrp30 Mouse, Adiponectin Mouse Recombinant Protein, HEK

PROTQ60994-2 Regular: 10ug
EUR 380.4
Description: The Acrp30 Mouse Recombinant is fused with FLAG tag having a total Mw of 26kDa.

Mouse, Resistin Mouse Recombinant Protein, His Tag

PROTQ99P87 Regular: 25ug
EUR 380.4
Description: Resistin Mouse is manufactured with signal sequence of phage fd (21aa) and C-terminal fusion of flagTag (10aa). Resistin Mouse Recombinant Flag-Tagged Fusion Protein is 13.7 kDa protein containing 93 amino acid residues of the Resistin Mouse and 31 additional amino acid residues - signal sequence of phage fd, flagTag (underlined).

Mouse Monoclonal Anti-Mouse CD5 (Ly 1.2), Biotin (Clone CG16) (mouse IgG2b)

MCD005-B 100 tests
EUR 562.8

Mouse Monoclonal Anti-Mouse CD5 (Ly 1.2), FITC (Clone CG16) (mouse IgG2b)

MCD005-F 100 tests
EUR 562.8

Mouse Monoclonal Anti-Mouse CD5 (Ly 1.2), PE (Clone CG16) (mouse IgG2b)

MCD005-PE 100 tests
EUR 562.8

Mouse Monoclonal Anti-Mouse CD160 mAb, Biotin, (clone CNX46-3), (mouse IgG2bk)

MCD160-B 100 tests
EUR 562.8

Mouse Monoclonal Anti-Mouse CD160 mAb, FITC, (clone CNX46-3), (mouse IgG2bk)

MCD160-F 50 Tests
EUR 489.6

Mouse Monoclonal Anti-Mouse CD160 mAb, Purified, (clone CNX46-3), (mouse IgG2bk)

MCD160-M 100 ug
EUR 578.4

Mouse Monoclonal Anti-Mouse CD160 mAb, PE, (clone CNX46-3), (mouse IgG2bk)

MCD160-PE 50 tests
EUR 416.4

Mouse Monoclonal Anti-Mouse CD5 (Ly 1.2), No Azide (Clone CG16) (mouse IgG2b)

MCD005-M 100 Tests
EUR 578.4

Pancreas Dissociation System 5 (Acinar, mouse parotid), Mouse

4-20375 ea Ask for price

Mouse IgG1 (FITC) / Mouse IgG1 (RPE) Isotype Control

abx405001-50tests 50 tests
EUR 760.8

Mouse IgG2a (FITC) / Mouse IgG2a (RPE) Isotype Control

abx405002-50tests 50 tests
EUR 744

Mouse IgG1 (FITC) / Mouse IgG2a (RPE) Isotype Control

abx405003-50tests 50 tests
EUR 744

Mouse IgG1 (FITC) / Mouse IgG1 (RPE) Isotype Control

abx405005-100tests 100 tests
EUR 744

Mouse Anti Mouse Cd28 Monoclonal Antibody,Low Endotoxin

CABT-48083MM 0.5 mg
EUR 1057.2

Mouse Anti-Mouse TIGIT Monoclonal antibody, clone 1G9

CABT-L4298-1mg 1 mg
EUR 1076.4

Mouse Anti-Mouse TIGIT Monoclonal antibody, clone 1G9

CABT-L4298-5mg 5 mg
EUR 2886

Mouse Anti-Mouse CD22 Monoclonal antibody, clone Cy34.1

CABT-L4309-1mg 1 mg
EUR 1076.4

Mouse Anti-Mouse CD22 Monoclonal antibody, clone Cy34.1

CABT-L4309-5mg 5 mg
EUR 2886

Mouse Anti-Mouse NK1.1 Monoclonal antibody, clone PK136

CABT-L4348-1mg 1 mg
EUR 1076.4

Mouse Anti-Mouse NK1.1 Monoclonal antibody, clone PK136

CABT-L4348-5mg 5 mg
EUR 2886

Mouse Anti-Mouse CD45.2 Monoclonal antibody, clone 104.2

CABT-L4528-1mg 1 mg
EUR 1076.4

Mouse Anti-Mouse CD45.2 Monoclonal antibody, clone 104.2

CABT-L4528-5mg 5 mg
EUR 2886

Mouse Anti Mouse Nc1.1 Monoclonal Antibody,Azide Free

DMABT-54458MM 1 mg
EUR 1513.2

IL3 Mouse, Interleukin-3 Mouse Recombinant Protein, sf9

PROTP01586-1 Regular: 5ug
EUR 380.4
Description: IL3 Mouse Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 148 amino acids (27-166 a.a.) and having a molecular mass of 16.7kDa (Migrates at 18-28kDa on SDS-PAGE under reducing conditions).;IL3 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

CTSB Mouse, Cathepsin-B Mouse Recombinant Protein, Active

PROTP10605-1 Regular: 10ug
EUR 380.4
Description: CTSB Mouse Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 330 amino acids (18-339a.a.) and having a molecular mass of 36.4kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa)._x000D_ CTSB is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

CST3 Mouse, Cystatin-C Mouse Recombinant Protein, sf9

PROTP21460-2 Regular: 10ug
EUR 380.4
Description: CST3 produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 126 amino acids (21-140a.a.) and having a molecular mass of 14.2kDa. (Molecular size on SDS-PAGE will appear at approximately 13.5-18kDa).;CST3 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

CST3 Mouse, Cystatin-C, Recombinant Protein Mouse Active

PROTP21460-3 Regular: 10ug
EUR 380.4
Description: CST3 Mouse produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 126 amino acids (21-140 a.a.) and having a molecular mass of 14.2kDa (Molecular size on SDS-PAGE will appear at approximately 13.5-18kDa).;CST3 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

CST3 Mouse, Cystatin-C Mouse Recombinant Protein, Active

PROTP21460-4 Regular: 10ug
EUR 380.4
Description: CST3 Mouse produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 126 amino acids (21-140 a.a.) and having a molecular mass of 14.2kDa (Molecular size on SDS-PAGE will appear at approximately 13.5-18kDa).;CST3 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

Acrp30 Mouse, Adiponectin Mouse Recombinant Protein, Trimeric form

PROTQ60994 Regular: 10ug
EUR 380.4
Description: Trimeric form of Acrp30 Mouse was expressed in HEK293 cells.;The cysteine 39 was replaced with alanine (C39A) 9. mAd-C39A can only form trimer, but not hexamer or HMW form.

Acrp30 Mouse, Adiponectin Mouse Recombinant Protein, His Tag

PROTQ60994-3 Regular: 25ug
EUR 380.4
Description: The Adiponectin Mouse is created as a recombinant protein with a 21 a.a N-terminal fusion of His Tag. The Adiponectin His-Tagged Fusion Protein, produced in E. coli, is a 27.2kDa protein containing 251 amino acid residues of the Acrp30 Mouse, 18-247 amino acids.

Mouse Recombinant DHFR

6383-100
EUR 568.8

SF20, mouse recombinant

4334-10
EUR 320.4

SF20, mouse recombinant

4334-1000
EUR 9456

Mouse IgG (FITC)

65C-CH1002 1 mg
EUR 283.2
Description: Purified Mouse IgG FITC conjugate

Mouse IgG (HRP)

65C-CH1003 1 mg
EUR 309.6
Description: Purified Mouse IgG HRP conjugate

Mouse IgG1 (FITC)

65C-CH1005 100 µg
EUR 271.2
Description: Purified Mouse IgG1 FITC conjugate

Mouse IgG1 (HRP)

65C-CH1006 100 µg
EUR 309.6
Description: Purified Mouse IgG1 HRP conjugate

Mouse IgG2a (FITC)

65C-CH1008 100 µg
EUR 271.2
Description: Purified Mouse IgG2a FITC conjugate

Mouse IgG2a (HRP)

65C-CH1009 100 µg
EUR 309.6
Description: Purified Mouse IgG2a HRP conjugate

Mouse IgG2b (FITC)

65C-CH1011 100 µg
EUR 271.2
Description: Purified Mouse IgG2b FITC conjugate

Mouse IgG3 (FITC)

65C-CH1014 100 µg
EUR 271.2
Description: Purified Mouse IgG3 FITC conjugate

Mouse IgG3 (HRP)

65C-CH1015 100 µg
EUR 309.6
Description: Purified Mouse IgG3 HRP conjugate

Mouse IgG2b (HRP)

65C-CH1022 100 µg
EUR 309.6
Description: Purified Mouse IgG2b HRP conjugate

DPPIV (Mouse) Antibody

6694-50
EUR 548.4

Recombinant Mouse Endoglin

7-00301 2µg Ask for price

Recombinant Mouse Endoglin

7-00302 10µg Ask for price

Recombinant Mouse Endoglin

7-00303 100µg Ask for price

Recombinant Mouse Leptin

7-01144 200µg Ask for price

Recombinant Mouse Leptin

7-01145 1mg Ask for price

Recombinant Mouse Leptin

7-01146 5mg Ask for price

Recombinant Mouse Noggin

7-01309 5µg Ask for price

Recombinant Mouse Noggin

7-01310 20µg Ask for price

Recombinant Mouse Noggin

7-01311 1mg Ask for price

Recombinant Mouse Prolactin

7-01417 10µg Ask for price

Recombinant Mouse Prolactin

7-01418 50µg Ask for price

Recombinant Mouse Prolactin

7-01419 1mg Ask for price

Recombinant Mouse Resistin

7-01528 5µg Ask for price

Recombinant Mouse Resistin

7-01529 25µg Ask for price

Recombinant Mouse Resistin

7-01530 1mg Ask for price

Recombinant Mouse Thrombopoietin

7-01693 2µg Ask for price

Recombinant Mouse Thrombopoietin

7-01694 10µg Ask for price

Recombinant Mouse Thrombopoietin

7-01695 1mg Ask for price

Recombinant Mouse Visfatin

7-01774 5µg Ask for price

Recombinant Mouse Visfatin

7-01775 25µg Ask for price

Recombinant Mouse Visfatin

7-01776 1mg Ask for price

Recombinant Mouse CXCL16

7-01804 5µg Ask for price

Recombinant Mouse CXCL16

7-01805 25µg Ask for price

Recombinant Mouse CXCL16

7-01806 1mg Ask for price

Recombinant Mouse Bax

7-04507 2µg Ask for price

Recombinant Mouse Bax

7-04508 10µg Ask for price

Recombinant Mouse Bax

7-04509 1mg Ask for price

Recombinant Mouse CD14

7-04714 2µg Ask for price

Recombinant Mouse CD14

7-04715 5µg Ask for price

Recombinant Mouse CD14

7-04716 10µg Ask for price

Mouse anti IgA1

10-I06A 1 mg
EUR 369.6
Description: Mouse anti IgA1 antibody

Mouse Leptin Antibody

11431-05011 150 ug
EUR 260.4

Mouse tPA Antibody

11632-05011 150 ug
EUR 260.4

Mouse Apotransferrin Antibody

14079-05011 150 ug
EUR 260.4

Mouse Adipose Lysate

1418 0.1 mg
EUR 229.2
Description: Adipose tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.

FABP4 Mouse mAb

A0120-100ul 100 ul
EUR 369.6

FABP4 Mouse mAb

A0120-200ul 200 ul
EUR 550.8

FABP4 Mouse mAb

A0120-20ul 20 ul Ask for price

FABP4 Mouse mAb

A0120-50ul 50 ul Ask for price

SirT1 Mouse mAb

A0127-100ul 100 ul
EUR 369.6

SirT1 Mouse mAb

A0127-200ul 200 ul
EUR 550.8

SirT1 Mouse mAb

A0127-20ul 20 ul Ask for price

SirT1 Mouse mAb

A0127-50ul 50 ul Ask for price

PHB Mouse mAb

A0156-100ul 100 ul
EUR 369.6

PHB Mouse mAb

A0156-200ul 200 ul
EUR 550.8

PHB Mouse mAb

A0156-20ul 20 ul Ask for price

PHB Mouse mAb

A0156-50ul 50 ul Ask for price

TOR1A Mouse mAb

A0170-100ul 100 ul
EUR 369.6

TOR1A Mouse mAb

A0170-200ul 200 ul
EUR 550.8

TOR1A Mouse mAb

A0170-20ul 20 ul Ask for price

TOR1A Mouse mAb

A0170-50ul 50 ul Ask for price


Toxoplasma encephalitis is an AIDS-defining condition. The decline in CD4 + T cell IFN-γ-producing AIDS is a major factor in silent reactivation of Toxoplasma gondii to replicate the active stage of infection. Therefore, it is important to characterize the CD4-independent mechanisms that limit acute T. gondii infection. We investigated the in vivo regulation of IFN-γ production by CD8 + T cells, DN T cells and NK cells in response to acute T. gondii infection.

Our data suggest that IFN-γ treatment by non-CD4 cells is dependent on both IL-12 and IL-18, and secretion of bioactive IL-18 in response to T. gondii parasite requires sensing inflammasome feasible by multiple redundant sensors in several hematopoietic cell types.

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