Methylation regulation of Antiviral host factors, Interferon Stimulated Genes (ISGs) and T-cell responses associated with natural HIV control

Methylation regulation of Antiviral host factors, Interferon Stimulated Genes (ISGs) and T-cell responses associated with natural HIV control

GWAS analysis and screening immune biomarkers have been identified host factors associated with in vivo HIV-1 control. However, there are gaps in knowledge about the mechanisms that regulate the expression of host factors. Here, we aimed to assess DNA methylation affects the natural host genome in HIV-1 control. For this purpose, the entire DNA methylome in 70 HIV-1 infected individuals not treated with either high (> 50,000 HIV-1 RNA copies / ml, n = 29) or low (<10,000 HIV-1 RNA copies / ml, n = viral load (PVL) level 41) plasma compared and identified 2649 different positions methylated (DMP).

Of these, the forest classification model randomly selected 55 DMP were correlated with viral (PVL and proviral levels) and adaptive immunity parameters of HIV-1 specific (IFNg-T cell responses and neutralizing capacity of antibodies). Then, cluster and functional analysis identified two groups of DMP: cluster 1 contained the gene hypo-methylated involved in antiviral and interferon response (eg PARP9, MX1 and USP18) in individuals with high viral loads while in cluster 2, genes associated with T follicular helper cells (TFH) commitments (eg CXCR5 and TCF7) hyper-methylated in the same group of people with uncontrolled infection.

For selected genes, mRNA levels were negatively correlated with DNA methylation, which states the epigenetic regulation of gene expression. Furthermore, expression of this gene signature was also confirmed in the early stages of chronic infection, including untreated, treated and elite controllers ART HIV-1 infected individuals (n = 37). These data provide the first evidence that the critical host genes involved in the immune control of the virus is under the regulation of methylation in HIV-1 infection. This insight may offer a new opportunity to identify novel mechanisms in vivo control of the virus and may prove important for the development of future therapeutic interventions aimed at HIV-1 cure.

 Methylation regulation of Antiviral host factors, Interferon Stimulated Genes (ISGs) and T-cell responses associated with natural HIV control
Methylation regulation of Antiviral host factors, Interferon Stimulated Genes (ISGs) and T-cell responses associated with natural HIV control

Heat stress in the oocyte or zygote compromise embryonic development, production interferon tau damage and increases reactive oxygen species and oxidative stress in cattle embryos produced in vitro

Interferon tau (IFNT) is a cytokine that is responsible for the recognition of pregnant women in ruminants and play the role of embryo-maternal communication modulation in the oviduct induces local response of immune cells. We aimed to investigate the production of IFNT, reactive oxygen species and oxidative stress under the influence of heat stress (HS) during the different stages of cow in vitro embryo production.

HS was set up when the temperature is gradually raised from 38.5 ° C to 40.5 ° C in a laboratory incubator, sustained for 6 hours, and reduced back to 38.5 ° C. To overcome the effects of HS on IFNT production, reactive oxygen species, and oxidative stress, ovaries from a slaughterhouse that is used in accordance with the treatment: a control group (38.5 ° C); oocytes mature under the HS; fertilized oocytes under HS; zygotes were cultured on the first day under the HS; and delivered to the HS cell in oocyte maturation, fertilization and embryo culture first day.

Antibody for Human IFN gamma

SPC-1297D-A390 0.1ml
EUR 433.2
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to ATTO 390.

Antibody for Human IFN gamma

SPC-1297D-A488 0.1ml
EUR 432
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to ATTO 488.

Antibody for Human IFN gamma

SPC-1297D-A565 0.1ml
EUR 432
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to ATTO 565.

Antibody for Human IFN gamma

SPC-1297D-A594 0.1ml
EUR 432
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to ATTO 594.

Antibody for Human IFN gamma

SPC-1297D-A633 0.1ml
EUR 432
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to ATTO 633.

Antibody for Human IFN gamma

SPC-1297D-A655 0.1ml
EUR 432
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to ATTO 655.

Antibody for Human IFN gamma

SPC-1297D-A680 0.1ml
EUR 432
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to ATTO 680.

Antibody for Human IFN gamma

SPC-1297D-A700 0.1ml
EUR 432
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to ATTO 700.

Antibody for Human IFN gamma

SPC-1297D-ALP 0.1ml
EUR 426
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to Alkaline Phosphatase.

Antibody for Human IFN gamma

SPC-1297D-APC 0.1ml
EUR 430.8
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to APC .

Antibody for Human IFN gamma

SPC-1297D-APCCY7 0.1ml
EUR 518.4
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to APC/Cy7.

Antibody for Human IFN gamma

SPC-1297D-BI 0.1ml
EUR 428.4
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to Biotin.

Antibody for Human IFN gamma

SPC-1297D-DY350 0.1ml
EUR 523.2
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to Dylight 350.

Antibody for Human IFN gamma

SPC-1297D-DY405 0.1ml
EUR 494.4
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to Dylight 405.

Antibody for Human IFN gamma

SPC-1297D-DY488 0.1ml
EUR 471.6
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to Dylight 488.

Antibody for Human IFN gamma

SPC-1297D-DY594 0.1ml
EUR 476.4
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to Dylight 594.

Antibody for Human IFN gamma

SPC-1297D-DY633 0.1ml
EUR 464.4
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to Dylight 633.

Antibody for Human IFN gamma

SPC-1297D-FITC 0.1ml
EUR 423.6
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to FITC.

Antibody for Human IFN gamma

SPC-1297D-HRP 0.1ml
EUR 418.8
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to HRP.

Antibody for Human IFN gamma

SPC-1297D-P594 0.1ml
EUR 440.4
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to PE/ATTO 594.

Antibody for Human IFN gamma

SPC-1297D-PCP 0.1ml
EUR 430.8
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to PerCP.

Antibody for Human IFN gamma

SPC-1297D-RPE 0.1ml
EUR 429.6
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to RPE .

Antibody for Human IFN gamma

SPC-1297D-STR 0.1ml
EUR 430.8
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to Streptavidin.

Recombinant Human IFN gamma

EPT166 50ug
EUR 167.4
Description: Recombinant Human Interferon Gamma is produced by our Mammalian expression system and the target gene encoding Gln24-Gln166 is expressed.

Human IFN gamma ELISA Kit

55R-1590 1 kit
EUR 483.6
Description: ELISA kit for detection of IFN gamma in the research laboratory

Human IFN gamma ELISA Set

M851560005 1 unit
EUR 430.79

Human IFN gamma ELISA Set

M851560020 1 unit
EUR 843.16

Human IFN gamma ELISA Kit

M950000192 1 unit
EUR 591.37

Anti-rat IFN gamma Antibody

RP1001 100ug/vial
EUR 400.8

Human IFN gamma ELISpot Set

M856051001 1 unit
EUR 209.52

Human IFN gamma ELISpot Set

M856051010 1 unit
EUR 1193.1

Human IFN gamma ELISpot Set

M856051020 1 unit
EUR 1722.04

HUMAN IFN GAMMA ELISPOT KIT

MPC6051005 1 unit
EUR 1224.14

Human IFN gamma ELISpot Pair

M869060010 1 unit
EUR 1070.25

IFN gamma antibody

10-7923 1 mg
EUR 516
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10-7924 1 mg
EUR 516
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10-I61a 250 ug
EUR 1363.2
Description: Mouse monoclonal IFN gamma antibody (neutralizing)

IFN gamma antibody

10-I61B 100 ug
EUR 364.8
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10-I61C 500 ug
EUR 327.6
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10-I67A 100 ug
EUR 169.2
Description: Rat monoclonal IFN gamma antibody

IFN gamma antibody

10R-1882 100 ul
EUR 418.8
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10R-2118 100 ul
EUR 483.6
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10R-6643 50 ug
EUR 184.8
Description: Rat monoclonal IFN gamma antibody

IFN gamma antibody

10R-6644 50 ug
EUR 184.8
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10R-6645 50 ug
EUR 184.8
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10R-7733 500 ug
EUR 678
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10R-7764 500 ug
EUR 678
Description: Rat monoclonal IFN gamma antibody

IFN gamma antibody

10R-I101B 500 ug
EUR 327.6
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10R-I101c 500 ug
EUR 548.4
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10R-I157a 500 ug
EUR 716.4
Description: Rat monoclonal IFN gamma antibody

IFN gamma antibody

20-IR67 2 x 10^4 units
EUR 548.4
Description: Rabbit polyclonal IFN gamma antibody

IFN gamma antibody

70R-IG025 50 ug
EUR 327.6
Description: Affinity purified Goat polyclonal IFN gamma antibody

IFN gamma antibody

70R-IR001 100 ug
EUR 392.4
Description: Affinity purified Rabbit polyclonal IFN gamma antibody

IFN gamma antibody

70R-IR054 50 ug
EUR 327.6
Description: Affinity purified Rabbit polyclonal IFN gamma antibody

IFN gamma antibody

70-IR18 50 ug
EUR 366
Description: Affinity purified Rabbit polyclonal IFN gamma antibody

IFN gamma antibody

70R-12265 200 ug
EUR 483.6
Description: Rabbit polyclonal IFN gamma antibody

IFN gamma antibody

70R-12266 100 ug
EUR 483.6
Description: Rabbit polyclonal IFN gamma antibody

IFN gamma antibody

70R-13664 100 ug
EUR 438
Description: Affinity purified Rabbit polyclonal IFN gamma antibody

IFN gamma antibody

70R-13665 100 ug
EUR 438
Description: Affinity purified Rabbit polyclonal IFN gamma antibody

IFN gamma antibody

70R-14032 100 ug
EUR 366
Description: Affinity purified Rabbit polyclonal IFN gamma antibody

IFN gamma antibody

70R-49894 100 ul
EUR 292.8
Description: Purified Polyclonal IFN gamma antibody

IFN gamma Antibody

5116-200 each
EUR 379.2

IFN gamma Antibody

5117-100 each
EUR 379.2

IFN gamma Antibody

R31456 100 ug
EUR 356.15
Description: IFN gamma is an inflammatory cytokine that has been implicated in the development of fibrosis in inflamed tissues. IFN gamma is also produced by natural killer (NK) cells and most prominently by CD8 cytotoxic T cells, and is vital for the control of microbial pathogens. Interferon gamma is believed to be crucial for host defence against many infections.

IFN gamma Antibody

E8RT1321 100ul
EUR 225
Description: Available in various conjugation types.

IFN gamma Antibody

E38PA1575 100ul
EUR 225
Description: Available in various conjugation types.

Recombinant Human IFN gamma Protein

R00393 100ug/vial
EUR 352.8

Human IFN gamma Recombinant Protein

R00393-7 5ug/vial
EUR 310.8
Description: IFN-gamma, or type II interferon, is a cytokine that is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Human IFN gamma Recombinant Protein is purified IFN gamma produced in yeast.

IFN-Gamma/ Rat IFN- Gamma ELISA Kit

ELA-E0049r 96 Tests
EUR 1063.2

Human Cytokine IFN Gamma Recombinant

IHUIFNGRC25UG each
EUR 507
Description: Human Cytokine IFN Gamma Recombinant

Human Cytokine IFN Gamma Recombinant

IHUIFNGRC5UG each
EUR 283
Description: Human Cytokine IFN Gamma Recombinant

Human IFN-gamma(Interferon Gamma) ELISA Kit

STJ150109 1 kit
EUR 494.4
Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of IFN-gamma in human serum, plasma and other biological fluids

IFN -gamma R2 ELISA KIT|Human

EF010951 96 Tests
EUR 826.8

IFN gamma, Interferon gamma, rat

RC257-17+A114 20ug
EUR 121.6

Human IFN gamma PicoKine ELISA Kit

EK0373 96 wells
EUR 510
Description: For quantitative detection of human IFN gamma in cell culture supernates and serum.

Recombinant Human IFN gamma (E. coli)

EPT184 50ug
EUR 113.4
Description: Recombinant Human Interferon Gamma is produced by our E.coli expression system and the target gene encoding Gln24-Gln166 is expressed.

HUMAN IFN GAMMA ELISPOT KIT 1X96DET

MPC6051001 1 unit
EUR 306.06

IFN gamma,Swine

E34M012S 5 μg
EUR 295

IFN gamma,Mouse

E34M052M 20 μg
EUR 155

IFN gamma antibody (PE)

61R-1413 100 ug
EUR 528
Description: Mouse monoclonal IFN gamma antibody (PE)

IFN Gamma R2 antibody

70R-6702 50 ug
EUR 560.4
Description: Rabbit polyclonal IFN Gamma R2 antibody

IFN gamma protein

30R-1053 100 ug
EUR 268.8
Description: Purified recombinant Human IFN gamma protein

IFN gamma protein

30R-2186 25 ug
EUR 249.6
Description: Purified recombinant Human IFN gamma protein

IFN gamma protein

30R-2267 100 ug
EUR 457.2
Description: Purified recombinant Human IFN gamma protein

IFN gamma protein

30R-2341 20 ug
EUR 182.4
Description: Purified recombinant Human IFN gamma protein

IFN gamma protein

30R-2342 20 ug
EUR 268.8
Description: Purified recombinant Human IFN gamma protein

IFN gamma protein

30R-2343 20 ug
EUR 274.8
Description: Purified recombinant Human IFN gamma protein

IFN gamma protein

30R-3133 50 ug
EUR 308.4
Description: Purified recombinant IFN gamma protein

IFN gamma protein

30R-3159 50 ug
EUR 308.4
Description: Purified recombinant IFN gamma protein

IFN gamma protein

30R-3160 50 ug
EUR 308.4
Description: Purified recombinant IFN gamma protein

IFN gamma protein

30R-AI065 20 ug
EUR 159.6
Description: Purified recombinant Human IFN gamma protein

IFN gamma protein

30R-AI069 100 ug
EUR 327.6
Description: Purified recombinant Human IFN gamma protein

IFN gamma protein

30-1386 500 ug
EUR 470.4
Description: Recombinant IFN gamma protein

IFN gamma Protein

abx060288-100ug 100 ug
EUR 794.4

IFN gamma antibody (FITC)

61R-1174 100 ug
EUR 418.8
Description: Mouse monoclonal IFN gamma antibody (FITC)

IFN gamma antibody (FITC)

60R-1163 100 ug
EUR 392.4
Description: Rabbit polyclonal IFN gamma antibody (FITC)

Human IFN -gamma R2(Interferon Gamma Receptor-2) ELISA Kit

EH4152 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens ;Sensitivity: 0.188 ng/ml

Human IFN -gamma R2(Interferon Gamma Receptor-2) ELISA Kit

E39EH4152 96T
EUR 595

IFN gamma antibody (biotin)

60R-IG001bt 50 ug
EUR 457.2
Description: Goat polyclonal IFN gamma antibody (biotin)

IFN gamma antibody (biotin)

60R-IR001bt 50 ug
EUR 457.2
Description: Rabbit polyclonal IFN gamma antibody (biotin)

IFN gamma antibody (biotin)

61R-1660 50 ug
EUR 230.4
Description: Rat monoclonal IFN gamma antibody (biotin)

IFN gamma antibody (biotin)

61R-1661 50 ug
EUR 230.4
Description: Mouse monoclonal IFN gamma antibody (biotin)

IFN gamma antibody (biotin)

61R-I101bBT 500 ug
EUR 548.4
Description: Mouse monoclonal IFN gamma antibody (biotin)

Anti-IFN gamma PE

1P-706-T025 25 tests
EUR 168

Anti-IFN gamma PE

1P-706-T100 100 tests
EUR 288

Polyclonal IFN gamma Antibody

APR00266G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human IFN gamma . This antibody is tested and proven to work in the following applications:

Polyclonal IFN gamma Antibody

APR00267G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human IFN gamma . This antibody is tested and proven to work in the following applications:

Anti-IFN gamma APC

1A-706-T025 25 tests
EUR 168

Anti-IFN gamma APC

1A-706-T100 100 tests
EUR 288

Anti-IFN gamma FITC

1F-706-T025 25 tests
EUR 146.4

Anti-IFN gamma FITC

1F-706-T100 100 tests
EUR 244.8

Human IFN gamma Recombinant Protein Lyophilized

IHUIFNGRLY20UG each
EUR 341
Description: Human IFN gamma Recombinant Protein Lyophilized

IFN-Gamma ab/ Rat IFN- Gamma ab ELISA Kit

ELA-E1716r 96 Tests
EUR 1063.2

Anti-IFN gamma Antibody

E38A8952 100ug/100ul
EUR 225
Description: Available in various conjugation types.

IFN gamma, Interferon gamma, murine (mouse)

RC237-17 20ug
EUR 125.26

Anti-IFN gamma Biotin

1B-706-C025 0.025 mg
EUR 146.4

Anti-IFN gamma Biotin

1B-706-C100 0.1 mg
EUR 244.8

IFN gamma antibody (allophycocyanin)

61R-1794 100 ug
EUR 548.4
Description: Mouse monoclonal IFN gamma antibody (allophycocyanin)

Anti-IFN gamma Purified

11-481-C025 0.025 mg
EUR 118.8

Anti-IFN gamma Purified

11-481-C100 0.1 mg
EUR 189.6

Anti-IFN gamma Purified

11-705-C025 0.025 mg
EUR 118.8

Anti-IFN gamma Purified

11-705-C100 0.1 mg
EUR 189.6

Anti-IFN gamma Purified

11-706-C025 0.025 mg
EUR 118.8

Anti-IFN gamma Purified

11-706-C100 0.1 mg
EUR 189.6

IFN gamma ELISA Kit

55R-M1921clb 96 tests
EUR 837.6
Description: Pelikase ELISA kit for detection of Human IFN Gamma in the research laboratory

IFN gamma ELISA Kit

55R-M1933clb 288 tests
EUR 805.2
Description: Pelikase Compact ELISA kit for detection of Human IFN Gamma in the research laboratory

Human IFN-γ (Interferon Gamma) ELISA Kit

EKE60102-5x96T 5x96T
EUR 2667.6

Human IFN-γ (Interferon Gamma) ELISA Kit

EKE60102-96T 96T
EUR 561.6

Human IFN-γ(Interferon gamma) ELISA Kit

EKF57052-48T 48T
EUR 396.9

Human IFN-γ(Interferon gamma) ELISA Kit

EKF57052-5x96T 5x96T
EUR 2693.25

Human IFN-γ(Interferon gamma) ELISA Kit

EKF57052-96T 96T
EUR 567

IFN gamma 1 protein

30R-AI068 20 ug
EUR 327.6
Description: Purified recombinant Human IFN gamma 1 protein

IFN gamma 2 protein

30R-AI150 20 ug
EUR 327.6
Description: Purified recombinant Human IFN gamma 2 protein

IFN gamma Rabbit mAb

A23152 200μL
EUR 1557.4
Description: A synthetic peptide corresponding to a sequence within amino acids 350-450 of human Radixin (P35241).

IFN gamma Rabbit mAb

A23929 20μL
EUR 213.2
Description: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IKKβ (O14920).

RAT IFN GAMMA ELISPOT

MPC7011001 1 unit
EUR 306.06

Human Interferon Gamma (IFN-γ) CLIA Kit

abx195803-96tests 96 tests
EUR 990

IFN gamma ELISpot Assay Kit (Human) (OKDB00011)

OKDB00011 1x96Wells
EUR 638.4
Description: Description of target: This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISpot Immunoassay;Sensitivity:

Human Interferon, Gamma (IFN-γ) ELISA Kit

DEIABL-CK4 96T
EUR 752.4
Description: This CD Interferon Gamma ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Human IFN-γ. This ELISA kit for research use only, not for therapeutic or diagnostic applications!

Human Interferon Gamma (IFN-γ)  ELISA Kit

NSL1963Hu 96 wells
EUR 468

IFN gamma protein (Mouse)

30R-2183 10 ug
EUR 340.8
Description: Purified recombinant Mouse IFN gamma protein

IFN gamma protein (Mouse)

30R-2264 100 ug
EUR 651.6
Description: Purified recombinant Mouse IFN gamma protein

IFN gamma protein (Mouse)

30R-AI070x 100 ug
EUR 327.6
Description: Purified recombinant Mouse IFN gamma protein

Duck gamma interferon (IFN - gamma) ELISA Kit

QY-E150033 96T
EUR 590.4

MURINE IFN GAMMA ELISPOT

MPC2031001 1 unit
EUR 306.06

IFN gamma Blocking Peptide

20-abx062769
  • EUR 326.40
  • EUR 493.20
  • 1 mg
  • 5 mg

IFN gamma Blocking Peptide

DF6045-BP 1mg
EUR 234

CLIA kit for Human IFN-? (Interferon Gamma)

E-CL-H0107 1 plate of 96 wells
EUR 700.8
Description: A sandwich CLIA kit for quantitative measurement of Human IFN-? (Interferon Gamma) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human IFN-? (Interferon Gamma)

E-EL-H0108 1 plate of 96 wells
EUR 452.4
Description: A sandwich ELISA kit for quantitative measurement of Human IFN-? (Interferon Gamma) in samples from Serum, Plasma, Cell supernatant

IFN gamma Recombinant Protein

40-277-002mg 0.02 mg
EUR 311.1
Description: IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ species-specific and is biologically active only in human and primate cells. Recombinant human IFN-γ is a 16.7 kDa protein containing 143 amino acid residues.

IFN gamma Recombinant Protein

40-277-01mg 0.1 mg
EUR 437.1
Description: IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ species-specific and is biologically active only in human and primate cells. Recombinant human IFN-γ is a 16.7 kDa protein containing 143 amino acid residues.

IFN gamma Recombinant Protein

40-449-002mg 0.02 mg
EUR 311.1
Description: IFN-gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-gamma receptors are present in most immune cells, which respond to IFN-gamma signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-gamma signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulates the antigen-specific phases of the immune response. Additionally, IFN-gamma stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-gamma species-specific and is biologically active only in human and primate cells. Recombinant murine IFN-gamma is a 15.6 kDa protein containing 134 amino acid residues.

IFN gamma Recombinant Protein

40-449-01mg 0.1 mg
EUR 437.1
Description: IFN-gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-gamma receptors are present in most immune cells, which respond to IFN-gamma signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-gamma signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulates the antigen-specific phases of the immune response. Additionally, IFN-gamma stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-gamma species-specific and is biologically active only in human and primate cells. Recombinant murine IFN-gamma is a 15.6 kDa protein containing 134 amino acid residues.

IFN gamma Recombinant Protein

40-472-002mg 0.02 mg
EUR 311.1
Description: IFN-gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-gamma receptors are present in most immune cells, which respond to IFN-gamma signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-gamma signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-gamma stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-gamma is species-specific and is biologically active only in human and primate cells. Recombinant rat IFN-gamma is a 15.6 kDa protein containing 135 amino acid residues.

IFN gamma Recombinant Protein

40-472-01mg 0.1 mg
EUR 437.1
Description: IFN-gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-gamma receptors are present in most immune cells, which respond to IFN-gamma signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-gamma signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-gamma stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-gamma is species-specific and is biologically active only in human and primate cells. Recombinant rat IFN-gamma is a 15.6 kDa protein containing 135 amino acid residues.

IFN gamma Recombinant Protein

91-012 0.05 mg
EUR 374.1
Description: IFN gamma is the major interferon produced by mitogenically or antigenically stimulated lymphocytes. It is structurally different from type I interferon and its major activity is immunoregulation. It has been implicated in the expression of class II histocompatibility antigens in cells that do not normally produce them, leading to autoimmune disease. Interferon gamma is produced mainly byT-cells and natural killer cells activated by antigens, mitogens, or alloantigens. It is produced by lymphocytes expressing the surface antigens CD4 and CD8. IFN gamma synthesis is induced by IL-2, FGF-basic, and EGF.

IFN gamma Recombinant Protein

91-591 0.05 mg
EUR 374.1
Description: Mouse Ifng is a secreted protein which belongs to the type I I (or gamma) interferon family. IFNG is produced by lymphocytes and activated by specific antigens or mitogens. In addition to having antiviral activity, IFNG also has important immunoregulatory functions. It is a potent activator of macrophages and has antiproliferative effects on transformed cells. It can potentiate the antiviral and antitumor effects of the type I interferons. Genetic variation in IFNG is associated with the risk of aplastic anemia (AA) which is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis.

IFN gamma Recombinant Protein

92-362 0.05 mg
EUR 437.1
Description: IFN gamma is the major interferon produced by mitogenically or antigenically stimulated lymphocytes. It is structurally different from type I interferon and its major activity is immunoregulation. It has been implicated in the expression of class II histocompatibility antigens in cells that do not normally produce them, leading to autoimmune disease. Interferon gamma is produced mainly byT-cells and natural killer cells activated by antigens, mitogens, or alloantigens. It is produced by lymphocytes expressing the surface antigens CD4 and CD8. IFN gamma synthesis is induced by IL-2, FGF-basic, and EGF.

IFN gamma Recombinant Protein

92-632 0.05 mg
EUR 437.1
Description: Mouse Ifng is a secreted protein which belongs to the type I I (or gamma) interferon family. IFNG is produced by lymphocytes and activated by specific antigens or mitogens. In addition to having antiviral activity, IFNG also has important immunoregulatory functions. It is a potent activator of macrophages and has antiproliferative effects on transformed cells. It can potentiate the antiviral and antitumor effects of the type I interferons. Genetic variation in IFNG is associated with the risk of aplastic anemia (AA) which is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis.

IFN gamma Recombinant Protein

92-633 0.05 mg
EUR 437.1
Description: Mouse Ifng is a secreted protein which belongs to the type I I (or gamma) interferon family. IFNG is produced by lymphocytes and activated by specific antigens or mitogens. In addition to having antiviral activity, IFNG also has important immunoregulatory functions. It is a potent activator of macrophages and has antiproliferative effects on transformed cells. It can potentiate the antiviral and antitumor effects of the type I interferons. Genetic variation in IFNG is associated with the risk of aplastic anemia (AA) which is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis.

Anti-IFN gamma PE-Cy7

T7-706-T025 25 tests
EUR 184.8

Anti-IFN gamma PE-Cy7

T7-706-T100 100 tests
EUR 321.6

Biotin anti-mouse CD119 (IFN gamma Receptor 1)

E16FMB119-100U 100 μg
EUR 606.67
Description: Available in various conjugation types.

Mouse anti-IFN gamma Antibody

DL99450A-100ul 100 ul
EUR 299
Description: Interferon gamma; IFN-gamma; Immune interferon

Mouse anti-IFN gamma Antibody

DL99450A-50ul 50 ul
EUR 210
Description: Interferon gamma; IFN-gamma; Immune interferon

Anti-IFN gamma PerCP-Cy5.5

T9-706-T025 25 tests
EUR 235.2

Anti-IFN gamma PerCP-Cy5.5

T9-706-T100 100 tests
EUR 422.4

Rabbit anti-IFN gamma Antibody

DL90575A-100ul 100 ul
EUR 270
Description: Interferon gamma; IFN-gamma; Immune interferon

Rabbit anti-IFN gamma Antibody

DL90575A-50ul 50 ul
EUR 189
Description: Interferon gamma; IFN-gamma; Immune interferon

Rabbit anti-IFN gamma Antibody

YLD4216-100ul 100 ul
EUR 320
Description: Rabbit polyclonal antibody to IFN gamma

Rabbit anti-IFN gamma Antibody

YLD4216-50ul 50 ul
EUR 200
Description: Rabbit polyclonal antibody to IFN gamma

Rat IFN gamma ELISA Kit

LF-EK50822 1×96T
EUR 777.6

anti-IFN gamma Receptor beta

YF-PA12610 50 ug
EUR 435.6
Description: Mouse polyclonal to IFN gamma Receptor beta

anti-IFN gamma Receptor beta

YF-PA12611 100 ul
EUR 483.6
Description: Rabbit polyclonal to IFN gamma Receptor beta

anti-IFN gamma Receptor beta

YF-PA12612 100 ug
EUR 483.6
Description: Rabbit polyclonal to IFN gamma Receptor beta

Mouse IFN gamma ELISA Kit

55R-1591 1 kit
EUR 748.8
Description: ELISA kit for detection of IFN gamma in the research laboratory

RAT IFN GAMMA ELISPOT KIT

MPC7011005 1 unit
EUR 1224.14

Murine IFN gamma ELISA Set

M861050020 1 unit
EUR 843.16

IFN gamma Rabbit PolymAb®

A23925 200μL
EUR 128.7
Description: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DISC1 (Q9NRI5).

Human IFN gamma Recombinant Protein Tag Free Lyophilized

IHUIFNGRTFLY50UG each
EUR 398
Description: Human IFN gamma Recombinant Protein Tag Free Lyophilized

IFN gamma High Sensitivity ELISA Kit (Human) (OKDB00041)

OKDB00041 1x96Wells
EUR 944.4
Description: Description of target: This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: < 0.69 pg/mL

Murine IFN gamma ELISpot Set

M862031010 1 unit
EUR 1193.1

Murine IFN gamma ELISpot Set

M862031020 1 unit
EUR 1722.04

MURINE IFN GAMMA ELISPOT KIT

MPC2031005 1 unit
EUR 1224.14

IFNGR2 Antibody / IFN gamma Receptor beta

F54438-0.08ML 0.08 ml
EUR 140.25
Description: IFNGR2 is the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection.

IFNGR2 Antibody / IFN gamma Receptor beta

F54438-0.4ML 0.4 ml
EUR 322.15
Description: IFNGR2 is the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection.

Ifngr2 Antibody / IFN gamma Receptor beta

RQ5981 100 ug
EUR 356.15
Description: Interferon gamma receptor 2 also known as IFN-gR2 is a protein which in humans is encoded by the IFNGR2 gene. It is mapped to 16 C3.3; 16 53.07 cM. This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.

IFN Gamma R2 Blocking Peptide

33R-9941 100 ug
EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of IFNGR2 antibody, catalog no. 70R-6702

Human Interferon Gamma Receptor (IFN-γR)  ELISA Kit

NSL1962Hu 96 wells
EUR 468

IFN gamma R1 Recombinant Protein

92-375 0.05 mg
EUR 437.1
Description: Interferon gamma receptor 1(IFNGR1) encoded by the IFNGR1 gene, is a single-pass type 1 membrane protein which belongs to the type II cytokine receptor family. IFNGR1 is phosphorylated at Ser/Thr residues after translation. IFNGR1 is a receptor for interferon gamma, two receptors bind one interferon gama dimer. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.

HS negatively affected the rate of cleavage and blastocyst, in all groups of HS. On Day 7, all HS-treated embryos showed a decrease IFNT gene and protein expression, whereas the reactive oxygen species increased compared with controls. In conclusion, early embryonic development is compromised because of the higher temperatures during in vitro oocyte maturation, fertilization, and / or the zygote stage has diminished IFNT expression and increased reactive oxygen species in cattle.

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