Methylation regulation of Antiviral host factors, Interferon Stimulated Genes (ISGs) and T-cell responses associated with natural HIV control

Methylation regulation of Antiviral host factors, Interferon Stimulated Genes (ISGs) and T-cell responses associated with natural HIV control

GWAS analysis and screening immune biomarkers have been identified host factors associated with in vivo HIV-1 control. However, there are gaps in knowledge about the mechanisms that regulate the expression of host factors. Here, we aimed to assess DNA methylation affects the natural host genome in HIV-1 control. For this purpose, the entire DNA methylome in 70 HIV-1 infected individuals not treated with either high (> 50,000 HIV-1 RNA copies / ml, n = 29) or low (<10,000 HIV-1 RNA copies / ml, n = viral load (PVL) level 41) plasma compared and identified 2649 different positions methylated (DMP).

Of these, the forest classification model randomly selected 55 DMP were correlated with viral (PVL and proviral levels) and adaptive immunity parameters of HIV-1 specific (IFNg-T cell responses and neutralizing capacity of antibodies). Then, cluster and functional analysis identified two groups of DMP: cluster 1 contained the gene hypo-methylated involved in antiviral and interferon response (eg PARP9, MX1 and USP18) in individuals with high viral loads while in cluster 2, genes associated with T follicular helper cells (TFH) commitments (eg CXCR5 and TCF7) hyper-methylated in the same group of people with uncontrolled infection.

For selected genes, mRNA levels were negatively correlated with DNA methylation, which states the epigenetic regulation of gene expression. Furthermore, expression of this gene signature was also confirmed in the early stages of chronic infection, including untreated, treated and elite controllers ART HIV-1 infected individuals (n = 37). These data provide the first evidence that the critical host genes involved in the immune control of the virus is under the regulation of methylation in HIV-1 infection. This insight may offer a new opportunity to identify novel mechanisms in vivo control of the virus and may prove important for the development of future therapeutic interventions aimed at HIV-1 cure.

 Methylation regulation of Antiviral host factors, Interferon Stimulated Genes (ISGs) and T-cell responses associated with natural HIV control
Methylation regulation of Antiviral host factors, Interferon Stimulated Genes (ISGs) and T-cell responses associated with natural HIV control

Heat stress in the oocyte or zygote compromise embryonic development, production interferon tau damage and increases reactive oxygen species and oxidative stress in cattle embryos produced in vitro

Interferon tau (IFNT) is a cytokine that is responsible for the recognition of pregnant women in ruminants and play the role of embryo-maternal communication modulation in the oviduct induces local response of immune cells. We aimed to investigate the production of IFNT, reactive oxygen species and oxidative stress under the influence of heat stress (HS) during the different stages of cow in vitro embryo production.

HS was set up when the temperature is gradually raised from 38.5 ° C to 40.5 ° C in a laboratory incubator, sustained for 6 hours, and reduced back to 38.5 ° C. To overcome the effects of HS on IFNT production, reactive oxygen species, and oxidative stress, ovaries from a slaughterhouse that is used in accordance with the treatment: a control group (38.5 ° C); oocytes mature under the HS; fertilized oocytes under HS; zygotes were cultured on the first day under the HS; and delivered to the HS cell in oocyte maturation, fertilization and embryo culture first day.

Anti-human IFN-gamma antibody

STJ15100056 250 µg
EUR 336
Description: This monoclonal antibody enables sensitive and specific detection of human IFN-γ in immunoassays such as ELISA and ELISpot.

Anti-human IFN-gamma antibody

STJ15100057 250 µg
EUR 367
Description: This monoclonal antibody enables sensitive and specific detection of human IFN-γ in immunoassays such as ELISA and ELISpot.

Anti-human IFN-gamma antibody

STJ15100058 1 ml
EUR 488
Description: This ALP-conjugated monoclonal antibody enables sensitive and specific detection of human IFN-γ in ELISpot.

Anti-human IFN-gamma antibody

STJ15100059 1 ml
EUR 488
Description: This HRP-conjugated monoclonal antibody enables sensitive and specific detection of human IFN-γ in immunoassays such as ELISA and ELISpot.

Anti-IFN-gamma antibody

STJ16100661 100 µg
EUR 604

Anti-IFN gamma Purified

11-481-C025 0.025 mg
EUR 99

Anti-IFN gamma Purified

11-481-C100 0.1 mg
EUR 158

Anti-IFN gamma Purified

11-705-C025 0.025 mg
EUR 99

Anti-IFN gamma Purified

11-705-C100 0.1 mg
EUR 158

Anti-IFN gamma Purified

11-706-C025 0.025 mg
EUR 99

Anti-IFN gamma Purified

11-706-C100 0.1 mg
EUR 158

Anti-IFN gamma APC

1A-706-T025 25 tests
EUR 140

Anti-IFN gamma APC

1A-706-T100 100 tests
EUR 240

Anti-IFN gamma Biotin

1B-706-C025 0.025 mg
EUR 122

Anti-IFN gamma Biotin

1B-706-C100 0.1 mg
EUR 204

Anti-IFN gamma FITC

1F-706-T025 25 tests
EUR 122

Anti-IFN gamma FITC

1F-706-T100 100 tests
EUR 204

Anti-IFN gamma PE

1P-706-T025 25 tests
EUR 140

Anti-IFN gamma PE

1P-706-T100 100 tests
EUR 240

Anti-IFN-gamma antibody

STJ98155 100 µl
EUR 234
Description: Mouse monoclonal to IFN-gamma.

Anti-IFN-gamma antibody

STJ98156 100 µl
EUR 234
Description: Mouse monoclonal to IFN-gamma.

Anti-IFN-gamma antibody

STJ93644 200 µl
EUR 197
Description: Rabbit polyclonal to IFN-gamma.

anti-IFN-gamma (3F1E3)

LF-MA30007 100 ul
EUR 445
Description: Mouse Monoclonal to IFN-gamma

anti-IFN-gamma (1B1A4)

LF-MA30137 100 ul
EUR 486
Description: Mouse Monoclonal to IFN-gamma

IFN-gamma, Human

HY-P7025 10ug
EUR 119

Anti-human/monkey IFN-gamma antibody

STJ15100060 250 µg
EUR 336
Description: This monoclonal antibody enables sensitive and specific detection of monkey IFN-γ in immunoassays such as ELISA and ELISpot.

IFN gamma, Interferon gamma, human

RC217-17 20ug
EUR 104.38

Anti-rat IFN gamma Antibody

RP1001 100ug/vial
EUR 334

Anti-IFN gamma PE-Cy7

T7-706-T025 25 tests
EUR 154

Anti-IFN gamma PE-Cy7

T7-706-T100 100 tests
EUR 268

Anti-IFN gamma PerCP-Cy5.5

T9-706-T025 25 tests
EUR 196

Anti-IFN gamma PerCP-Cy5.5

T9-706-T100 100 tests
EUR 352

Anti-rabbit IFN-gamma antibody

STJ15100000 250 µg
EUR 336
Description: This monoclonal antibody enables sensitive and specific detection of rabbit IFN-gamma (IFN-γ) in immunoassays such as ELISA and ELISpot

Anti-rabbit IFN-gamma antibody

STJ15100001 250 µg
EUR 367
Description: This monoclonal antibody enables sensitive and specific detection of rabbit IFN-gamma (IFN-γ) in immunoassays such as ELISA, ELISpot and Flow cytometry.

Anti-ferret IFN-gamma antibody

STJ15100004 250 µg
EUR 336
Description: This monoclonal antibody enables sensitive and specific detection of ferret IFN-γ in immunoassays such as ELISA and ELISpot.

Anti-ferret IFN-gamma antibody

STJ15100005 250 µg
EUR 367
Description: This monoclonal antibody enables sensitive and specific detection of ferret IFN-γ in immunoassays such as ELISA and ELISpot.

Anti-canine IFN-gamma antibody

STJ15100006 250 µg
EUR 336
Description: This monoclonal antibody enables sensitive and specific detection of canine (dog) Interferon-gamma (IFN-γ) in immunoassays such as ELISA and ELISpot.

Anti-canine IFN-gamma antibody

STJ15100007 250 µg
EUR 367
Description: This monoclonal antibody enables sensitive and specific detection of canine (dog) Interferon-gamma (IFN-γ) in immunoassays such as ELISA and ELISpot.

Anti-equine IFN-gamma antibody

STJ15100010 250 µg
EUR 336
Description: This monoclonal antibody enables sensitive and specific detection of equine (horse) Interferon-gamma (IFN-γ) in immunoassays such as ELISA and ELISpot.

Anti-equine IFN-gamma antibody

STJ15100011 250 µg
EUR 367
Description: This monoclonal antibody enables sensitive and specific detection of equine (horse) Interferon-gamma (IFN-γ) in immunoassays such as ELISA and ELISpot.

Anti-bovine IFN-gamma antibody

STJ15100012 250 µg
EUR 336
Description: This monoclonal antibody enables sensitive and specific detection of bovine IFN-γ in immunoassays such as ELISA and ELISpot.

Anti-bovine IFN-gamma antibody

STJ15100013 250 µg
EUR 367
Description: This monoclonal antibody enables sensitive and specific detection of bovine IFN-γ in immunoassays such as ELISA, ELISpot and Flow cytometry.

Anti-cat IFN-gamma antibody

STJ15100018 250 µg
EUR 336
Description: This monoclonal antibody enables sensitive and specific detection of cat (feline) IFN-γ in immunoassays such as ELISA and ELISpot.

Anti-cat IFN-gamma antibody

STJ15100019 250 µg
EUR 367
Description: This monoclonal antibody enables sensitive and specific detection of cat (feline) IFN-γ in immunoassays such as ELISA and ELISpot.

Anti-mouse IFN-gamma antibody

STJ15100038 250 µg
EUR 336
Description: This monoclonal antibody enables sensitive and specific detection of mouse IFN-γ in immunoassays such as ELISA and ELISpot.

Anti-mouse IFN-gamma antibody

STJ15100039 500 µg
EUR 527
Description: This monoclonal antibody is recommended for neutralization of mouse IFN-γ bioactivity.

Anti-mouse IFN-gamma antibody

STJ15100040 250 µg
EUR 367
Description: This monoclonal antibody enables sensitive and specific detection of mouse IFN-γ in immunoassays such as ELISA and ELISpot.

Anti-Mouse IFN-gamma antibody

STJ16100652 100 µg
EUR 604

Anti-Mouse IFN-gamma antibody

STJ16100653 100 µg
EUR 604

Anti-rat IFN-gamma antibody

STJ16101138 1 mL
EUR 730

Anti-IFN-gamma alpha antibody

STJ96760 200 µl
EUR 197
Description: Rabbit polyclonal to IFN-gammaRalpha.

Anti-IFN-gamma alpha antibody

STJ93645 200 µl
EUR 197
Description: IFN-gammaRalpha is a protein encoded by the IFNGR1 gene which is approximately 54,4 kDa. IFN-gammaRalpha is localised to the cell membrane and is involved in influenza A, Th17 cell differentiation, interferon gamma signalling, toxoplasmosis and type I interferon signalling pathways. It is a ligand-binding chain of the gamma interferon receptor which also includes IFNGR2. It associates with IFNGR2 to form a receptor for the cytokine interferon gamma. It is also associated with susceptibility to Helicobacter pylori infection. IFN-gammaRalpha is expressed in the nervous system, blood, spleen, lymph node and intestine. Mutations in the IFNGR1 gene result in immunodeficiency 27A and B. STJ93645 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of IFN-gammaRalpha protein.

anti-IFN gamma Receptor beta

YF-PA12610 50 ug
EUR 363
Description: Mouse polyclonal to IFN gamma Receptor beta

anti-IFN gamma Receptor beta

YF-PA12611 100 ul
EUR 403
Description: Rabbit polyclonal to IFN gamma Receptor beta

anti-IFN gamma Receptor beta

YF-PA12612 100 ug
EUR 403
Description: Rabbit polyclonal to IFN gamma Receptor beta

IFN-Gamma/ Rat IFN- Gamma ELISA Kit

ELA-E0049r 96 Tests
EUR 886

IFN-gamma, human recombinant

4116-100
EUR 256

IFN-gamma, human recombinant

4116-1000
EUR 1246

IFN-gamma, human recombinant

4116-20
EUR 137

Human Interferon-gamma (IFN-gamma) Antibody

20013-05011 150 ug
EUR 217

Human Interferon-gamma (IFN-gamma) Antibody

33161-05111 150 ug
EUR 261

IFN-gamma, Mouse

HY-P7071 10ug
EUR 131

IFN-gamma, Rat

HY-P7095 10ug
EUR 131

IFN-gamma/IFNγ

E21-014 10ug
EUR 343

IFN-gamma/IFNγ

E21-746 10ug
EUR 343

IFN-gamma/IFNγ

E21-I57 10ug
EUR 343

IFN gamma Protein

abx060288-100ug 100 ug
EUR 662

IFN gamma Antibody

DF6045 200ul
EUR 304
Description: IFN-γ Antibody detects endogenous levels of total IFN-γ.

rHu IFN-gamma

AK8293-0020 20µg Ask for price

rHu IFN-gamma

AK8293-0100 100µg Ask for price

rHu IFN-gamma

AK8293-1000 1mg Ask for price

IFN-gamma Antibody

BF0395 200ul
EUR 376
Description: IFN-gamma antibody detects endogenous levels of total IFN-gamma.

IFN gamma antibody

10R-6643 50 ug
EUR 154
Description: Rat monoclonal IFN gamma antibody

IFN gamma antibody

10R-6644 50 ug
EUR 154
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10R-6645 50 ug
EUR 154
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10R-7733 500 ug
EUR 565
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10R-7764 500 ug
EUR 565
Description: Rat monoclonal IFN gamma antibody

IFN gamma antibody

10R-I101B 500 ug
EUR 273
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10R-I101c 500 ug
EUR 457
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10R-I157a 500 ug
EUR 597
Description: Rat monoclonal IFN gamma antibody

IFN gamma antibody

20-IR67 2 x 10^4 units
EUR 457
Description: Rabbit polyclonal IFN gamma antibody

IFN gamma antibody

10R-1882 100 ul
EUR 349
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10R-2118 100 ul
EUR 403
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

70-IR18 50 ug
EUR 305
Description: Affinity purified Rabbit polyclonal IFN gamma antibody

IFN gamma antibody

10-7923 1 mg
EUR 430
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10-7924 1 mg
EUR 430
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10-I61a 250 ug
EUR 1136
Description: Mouse monoclonal IFN gamma antibody (neutralizing)

IFN gamma antibody

10-I61B 100 ug
EUR 304
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10-I61C 500 ug
EUR 273
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10-I67A 100 ug
EUR 141
Description: Rat monoclonal IFN gamma antibody

IFN gamma antibody

70R-12265 200 ug
EUR 403
Description: Rabbit polyclonal IFN gamma antibody

IFN gamma antibody

70R-12266 100 ug
EUR 403
Description: Rabbit polyclonal IFN gamma antibody

IFN gamma antibody

70R-13664 100 ug
EUR 365
Description: Affinity purified Rabbit polyclonal IFN gamma antibody

IFN gamma antibody

70R-13665 100 ug
EUR 365
Description: Affinity purified Rabbit polyclonal IFN gamma antibody

IFN gamma antibody

70R-14032 100 ug
EUR 305
Description: Affinity purified Rabbit polyclonal IFN gamma antibody

IFN gamma antibody

70R-49894 100 ul
EUR 244
Description: Purified Polyclonal IFN gamma antibody

IFN gamma antibody

70R-IG025 50 ug
EUR 273
Description: Affinity purified Goat polyclonal IFN gamma antibody

IFN gamma antibody

70R-IR001 100 ug
EUR 327
Description: Affinity purified Rabbit polyclonal IFN gamma antibody

IFN gamma antibody

70R-IR054 50 ug
EUR 273
Description: Affinity purified Rabbit polyclonal IFN gamma antibody

IFN gamma protein

30-1386 500 ug
EUR 392
Description: Recombinant IFN gamma protein

IFN gamma protein

30R-1053 100 ug
EUR 224
Description: Purified recombinant Human IFN gamma protein

IFN gamma protein

30R-2186 25 ug
EUR 208
Description: Purified recombinant Human IFN gamma protein

IFN gamma protein

30R-2267 100 ug
EUR 381
Description: Purified recombinant Human IFN gamma protein

IFN gamma protein

30R-2341 20 ug
EUR 152
Description: Purified recombinant Human IFN gamma protein

IFN gamma protein

30R-2342 20 ug
EUR 224
Description: Purified recombinant Human IFN gamma protein

IFN gamma protein

30R-2343 20 ug
EUR 229
Description: Purified recombinant Human IFN gamma protein

IFN gamma protein

30R-3133 50 ug
EUR 257
Description: Purified recombinant IFN gamma protein

IFN gamma protein

30R-3159 50 ug
EUR 257
Description: Purified recombinant IFN gamma protein

IFN gamma protein

30R-3160 50 ug
EUR 257
Description: Purified recombinant IFN gamma protein

IFN gamma protein

30R-AI065 20 ug
EUR 133
Description: Purified recombinant Human IFN gamma protein

IFN gamma protein

30R-AI069 100 ug
EUR 273
Description: Purified recombinant Human IFN gamma protein

IFN gamma Antibody

5116-200
EUR 316

IFN gamma Antibody

5117-100
EUR 316

Anti-cotton rat IFN-gamma antibody

STJ15100016 250 µg
EUR 336
Description: This monoclonal antibody enables sensitive and specific detection of cotton rat IFN-gamma (IFN-γ) in immunoassays such as ELISA and ELISpot.

Anti-cotton rat IFN-gamma antibody

STJ15100017 250 µg
EUR 367
Description: This monoclonal antibody enables sensitive and specific detection of cotton rat IFN-gamma (IFN-γ) in immunoassays such as ELISA, ELISpot, and flow cytometry.

Anti-IFN gamma Purified Low Endotoxin

12-705-C100 0.1 mg
EUR 158

Mouse Anti-IFN-gamma monoclonal antibody

CABT-BL8852 1.0 mg
EUR 944

Anti-IFN gamma Receptor beta (2D9)

YF-MA13694 100 ug
EUR 363
Description: Mouse monoclonal to IFN gamma Receptor beta

IFN gamma, Interferon gamma, rat

RC257-17+A114 20ug
EUR 101.33

IFN-Gamma ab/ Rat IFN- Gamma ab ELISA Kit

ELA-E1716r 96 Tests
EUR 886

Human IFN-gamma(Interferon Gamma) ELISA Kit

STJ150109 1 kit
EUR 412
Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of IFN-gamma in human serum, plasma and other biological fluids

Recombinant Human IFN-Gamma Protein

PROTP01579-4 100ug
EUR 317
Description: IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ species-specific and is biologically active only in human and primate cells. Recombinant human IFN-γ is a 16.8 kDa protein containing 144 amino acid residues.

Recombinant Human IFN gamma Protein

R00393 100ug/vial
EUR 294

Human IFN gamma Recombinant Protein

R00393-7 5ug/vial
EUR 259
Description: IFN-gamma, or type II interferon, is a cytokine that is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Human IFN gamma Recombinant Protein is purified IFN gamma produced in yeast.

IFN-gamma (CHO-expressed), Human

HY-P7025A 100ug
EUR 245

Antibody for Human IFN gamma

SPC-1297D 0.1ml
EUR 314
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is unconjugated.

Antibody for Human IFN gamma

SPC-1297D-A390 0.1ml
EUR 361
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to ATTO 390.

Antibody for Human IFN gamma

SPC-1297D-A488 0.1ml
EUR 360
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to ATTO 488.

Antibody for Human IFN gamma

SPC-1297D-A565 0.1ml
EUR 360
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to ATTO 565.

Antibody for Human IFN gamma

SPC-1297D-A594 0.1ml
EUR 360
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to ATTO 594.

Antibody for Human IFN gamma

SPC-1297D-A633 0.1ml
EUR 360
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to ATTO 633.

Antibody for Human IFN gamma

SPC-1297D-A655 0.1ml
EUR 360
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to ATTO 655.

Antibody for Human IFN gamma

SPC-1297D-A680 0.1ml
EUR 360
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to ATTO 680.

Antibody for Human IFN gamma

SPC-1297D-A700 0.1ml
EUR 360
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to ATTO 700.

Antibody for Human IFN gamma

SPC-1297D-ALP 0.1ml
EUR 355
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to Alkaline Phosphatase.

Antibody for Human IFN gamma

SPC-1297D-APC 0.1ml
EUR 359
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to APC .

Antibody for Human IFN gamma

SPC-1297D-APCCY7 0.1ml
EUR 432
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to APC/Cy7.

Antibody for Human IFN gamma

SPC-1297D-BI 0.1ml
EUR 357
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to Biotin.

Antibody for Human IFN gamma

SPC-1297D-DY350 0.1ml
EUR 436
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to Dylight 350.

Antibody for Human IFN gamma

SPC-1297D-DY405 0.1ml
EUR 412
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to Dylight 405.

Antibody for Human IFN gamma

SPC-1297D-DY488 0.1ml
EUR 393
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to Dylight 488.

Antibody for Human IFN gamma

SPC-1297D-DY594 0.1ml
EUR 397
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to Dylight 594.

Antibody for Human IFN gamma

SPC-1297D-DY633 0.1ml
EUR 387
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to Dylight 633.

Antibody for Human IFN gamma

SPC-1297D-FITC 0.1ml
EUR 353
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to FITC.

Antibody for Human IFN gamma

SPC-1297D-HRP 0.1ml
EUR 349
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to HRP.

Antibody for Human IFN gamma

SPC-1297D-P594 0.1ml
EUR 367
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to PE/ATTO 594.

Antibody for Human IFN gamma

SPC-1297D-PCP 0.1ml
EUR 359
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to PerCP.

Antibody for Human IFN gamma

SPC-1297D-RPE 0.1ml
EUR 358
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to RPE .

Antibody for Human IFN gamma

SPC-1297D-STR 0.1ml
EUR 359
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to Streptavidin.

Human IFN-gamma ELISA Kit

RK00015 96 Tests
EUR 521

Human IFN gamma ELISA Kit

55R-1590 1 kit
EUR 403
Description: ELISA kit for detection of IFN gamma in the research laboratory

IFN-gamma (Human) ELISA Kit

E4825-100 96 assays
EUR 581

Anti-Phospho-IFN-gamma alpha (Y457) antibody

STJ91086 200 µl
EUR 197
Description: Rabbit polyclonal to Phospho-IFN-gammaRalpha (Y457).

Rat Monoclonal Anti-Mouse IFN-gamma IgG

AB-16610 100 ug
EUR 347

Anti-IFN gamma Antibody [XMG1.2], APC-100ug

QAB83-APC-100ug 100ug
EUR 251

Anti-IFN gamma Antibody [XMG1.2], APC-25ug

QAB83-APC-25ug 25ug
EUR 141

Anti-IFN gamma Antibody [XMG1.2], Biotin-100ug

QAB83-B-100ug 100ug
EUR 208

Anti-IFN gamma Antibody [XMG1.2], Biotin-25ug

QAB83-B-25ug 25ug
EUR 115

Anti-IFN gamma Antibody [XMG1.2], FITC-100ug

QAB83-F-100ug 100ug
EUR 208

Anti-IFN gamma Antibody [XMG1.2], FITC-25ug

QAB83-F-25ug 25ug
EUR 123

Anti-IFN gamma Antibody [XMG1.2], PE-100ug

QAB83-PE-100ug 100ug
EUR 233

Anti-IFN gamma Antibody [XMG1.2], PE-25ug

QAB83-PE-25ug 25ug
EUR 131

Anti-IFN gamma Antibody [XMG1.2], V450-100ug

QAB83-V450-100ug 100ug
EUR 318

Anti-IFN gamma Antibody [XMG1.2], V450-25ug

QAB83-V450-25ug 25ug
EUR 182

IFN gamma, Interferon gamma, murine (mouse)

RC237-17 20ug
EUR 104.38

Canine IFN-gamma Antibody

33344-05111 150 ug
EUR 261

Polyclonal IFN gamma Antibody

APR00266G 0.1mg
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human IFN gamma . This antibody is tested and proven to work in the following applications:

Polyclonal IFN gamma Antibody

APR00267G 0.1mg
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human IFN gamma . This antibody is tested and proven to work in the following applications:

IFN-gamma GMP, CF

PR15124CF 100 ug
EUR 884

IFN-Gamma Polyclonal Antibody

ABP51594-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of IFN-? from Human. This IFN-? antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human IFN-?

IFN-Gamma Polyclonal Antibody

ABP51594-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of IFN-? from Human. This IFN-? antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human IFN-?

IFN-Gamma Polyclonal Antibody

ABP51594-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of IFN-? from Human. This IFN-? antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human IFN-?

IFN gamma Blocking Peptide

20-abx062769
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg

IFN-Gamma (IFNG) Antibody

abx139543-01mg 0.1 mg
EUR 356

IFN-Gamma (IFNG) Antibody

abx139544-01mg 0.1 mg
EUR 356

IFN-Gamma (IFNG) Antibody

abx139546-01mg 0.1 mg
EUR 356

IFN-gamma Antibody (FITC)

abx139547-100tests 100 tests
EUR 425

IFN-gamma Antibody (Biotin)

abx139550-01mg 0.1 mg
EUR 425

IFN-Gamma (IFNG) Antibody

abx139545-01mg 0.1 mg
EUR 356

IFN-Gamma (IFNG) Antibody

abx216157-100ug 100 ug
EUR 439

IFN-gamma, murine recombinant

P1015-.02 20 µg
EUR 161
Description: Interferon-gamma (IFN-?) is a prototype proinflammatory cytokine that is mainly produced by activated T, B and NK cells. IFN-? exists immunoregulatory activities, anti-viral activities, anti-proliferative and proinflammatory activities.

IFN-gamma, murine recombinant

P1015-.1 100 µg
EUR 313
Description: Interferon-gamma (IFN-?) is a prototype proinflammatory cytokine that is mainly produced by activated T, B and NK cells. IFN-? exists immunoregulatory activities, anti-viral activities, anti-proliferative and proinflammatory activities.

IFN-gamma, murine recombinant

P1015-1 1 mg
EUR 1581
Description: Interferon-gamma (IFN-?) is a prototype proinflammatory cytokine that is mainly produced by activated T, B and NK cells. IFN-? exists immunoregulatory activities, anti-viral activities, anti-proliferative and proinflammatory activities.

IFN gamma Blocking Peptide

DF6045-BP 1mg
EUR 195

IFN-gamma Blocking Peptide

BF0395-BP 1mg
EUR 195

IFN gamma ELISA Kit

55R-M1921clb 96 tests
EUR 698
Description: Pelikase ELISA kit for detection of Human IFN Gamma in the research laboratory

IFN gamma ELISA Kit

55R-M1933clb 288 tests
EUR 671
Description: Pelikase Compact ELISA kit for detection of Human IFN Gamma in the research laboratory

IFN gamma antibody (FITC)

61R-1174 100 ug
EUR 349
Description: Mouse monoclonal IFN gamma antibody (FITC)

IFN gamma antibody (PE)

61R-1413 100 ug
EUR 440
Description: Mouse monoclonal IFN gamma antibody (PE)

IFN gamma antibody (biotin)

61R-1660 50 ug
EUR 192
Description: Rat monoclonal IFN gamma antibody (biotin)

HS negatively affected the rate of cleavage and blastocyst, in all groups of HS. On Day 7, all HS-treated embryos showed a decrease IFNT gene and protein expression, whereas the reactive oxygen species increased compared with controls. In conclusion, early embryonic development is compromised because of the higher temperatures during in vitro oocyte maturation, fertilization, and / or the zygote stage has diminished IFNT expression and increased reactive oxygen species in cattle.

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