Methylation regulation of Antiviral host factors, Interferon Stimulated Genes (ISGs) and T-cell responses associated with natural HIV control

Methylation regulation of Antiviral host factors, Interferon Stimulated Genes (ISGs) and T-cell responses associated with natural HIV control

GWAS analysis and screening immune biomarkers have been identified host factors associated with in vivo HIV-1 control. However, there are gaps in knowledge about the mechanisms that regulate the expression of host factors. Here, we aimed to assess DNA methylation affects the natural host genome in HIV-1 control. For this purpose, the entire DNA methylome in 70 HIV-1 infected individuals not treated with either high (> 50,000 HIV-1 RNA copies / ml, n = 29) or low (<10,000 HIV-1 RNA copies / ml, n = viral load (PVL) level 41) plasma compared and identified 2649 different positions methylated (DMP).

Of these, the forest classification model randomly selected 55 DMP were correlated with viral (PVL and proviral levels) and adaptive immunity parameters of HIV-1 specific (IFNg-T cell responses and neutralizing capacity of antibodies). Then, cluster and functional analysis identified two groups of DMP: cluster 1 contained the gene hypo-methylated involved in antiviral and interferon response (eg PARP9, MX1 and USP18) in individuals with high viral loads while in cluster 2, genes associated with T follicular helper cells (TFH) commitments (eg CXCR5 and TCF7) hyper-methylated in the same group of people with uncontrolled infection.

For selected genes, mRNA levels were negatively correlated with DNA methylation, which states the epigenetic regulation of gene expression. Furthermore, expression of this gene signature was also confirmed in the early stages of chronic infection, including untreated, treated and elite controllers ART HIV-1 infected individuals (n = 37). These data provide the first evidence that the critical host genes involved in the immune control of the virus is under the regulation of methylation in HIV-1 infection. This insight may offer a new opportunity to identify novel mechanisms in vivo control of the virus and may prove important for the development of future therapeutic interventions aimed at HIV-1 cure.

 Methylation regulation of Antiviral host factors, Interferon Stimulated Genes (ISGs) and T-cell responses associated with natural HIV control
Methylation regulation of Antiviral host factors, Interferon Stimulated Genes (ISGs) and T-cell responses associated with natural HIV control

Heat stress in the oocyte or zygote compromise embryonic development, production interferon tau damage and increases reactive oxygen species and oxidative stress in cattle embryos produced in vitro

Interferon tau (IFNT) is a cytokine that is responsible for the recognition of pregnant women in ruminants and play the role of embryo-maternal communication modulation in the oviduct induces local response of immune cells. We aimed to investigate the production of IFNT, reactive oxygen species and oxidative stress under the influence of heat stress (HS) during the different stages of cow in vitro embryo production.

HS was set up when the temperature is gradually raised from 38.5 ° C to 40.5 ° C in a laboratory incubator, sustained for 6 hours, and reduced back to 38.5 ° C. To overcome the effects of HS on IFNT production, reactive oxygen species, and oxidative stress, ovaries from a slaughterhouse that is used in accordance with the treatment: a control group (38.5 ° C); oocytes mature under the HS; fertilized oocytes under HS; zygotes were cultured on the first day under the HS; and delivered to the HS cell in oocyte maturation, fertilization and embryo culture first day.

Anti-human IFN-gamma antibody

STJ15100057 250 µg
EUR 440.4
Description: This monoclonal antibody enables sensitive and specific detection of human IFN-γ in immunoassays such as ELISA and ELISpot.

Anti-human IFN-gamma antibody

STJ15100058 1 ml
EUR 585.6
Description: This ALP-conjugated monoclonal antibody enables sensitive and specific detection of human IFN-γ in ELISpot.

Anti-human IFN-gamma antibody

STJ15100059 1 ml
EUR 585.6
Description: This HRP-conjugated monoclonal antibody enables sensitive and specific detection of human IFN-γ in immunoassays such as ELISA and ELISpot.

Anti-human IFN gamma Antibody

RP1002 100ug/vial
EUR 400.8

Anti-IFN gamma Purified

11-705-C025 0.025 mg
EUR 118.8

Anti-IFN gamma Purified

11-705-C100 0.1 mg
EUR 189.6

Anti-IFN gamma Purified

11-706-C025 0.025 mg
EUR 118.8

Anti-IFN gamma Purified

11-706-C100 0.1 mg
EUR 189.6

Anti-IFN gamma APC

1A-706-T025 25 tests
EUR 168

Anti-IFN gamma APC

1A-706-T100 100 tests
EUR 288

Anti-IFN gamma Biotin

1B-706-C025 0.025 mg
EUR 146.4

Anti-IFN gamma Biotin

1B-706-C100 0.1 mg
EUR 244.8

Anti-IFN gamma FITC

1F-706-T025 25 tests
EUR 146.4

Anti-IFN gamma FITC

1F-706-T100 100 tests
EUR 244.8

Anti-IFN gamma PE

1P-706-T025 25 tests
EUR 168

Anti-IFN gamma PE

1P-706-T100 100 tests
EUR 288

Anti-IFN gamma Purified

11-481-C025 0.025 mg
EUR 118.8

Anti-IFN gamma Purified

11-481-C100 0.1 mg
EUR 189.6

anti-IFN-gamma (3F1E3)

LF-MA30007 100 ul
EUR 534
Description: Mouse Monoclonal to IFN-gamma

anti-IFN-gamma (1B1A4)

LF-MA30137 100 ul
EUR 583.2
Description: Mouse Monoclonal to IFN-gamma

Anti-IFN-gamma antibody

STJ93644 200 µl
EUR 236.4
Description: Rabbit polyclonal to IFN-gamma.

Anti-IFN-gamma antibody

STJ98155 100 µl
EUR 280.8
Description: Mouse monoclonal to IFN-gamma.

Anti-IFN-gamma antibody

STJ98156 100 µl
EUR 280.8
Description: Mouse monoclonal to IFN-gamma.

Anti-IFN-gamma antibody

STJ16100661 100 µg
EUR 724.8

IFN-gamma, Human

HY-P7025 10ug
EUR 142.8

IFN gamma, Interferon gamma, human

RC217-17 20ug
EUR 125.26

Anti-human/monkey IFN-gamma antibody

STJ15100060 250 µg
EUR 403.2
Description: This monoclonal antibody enables sensitive and specific detection of monkey IFN-γ in immunoassays such as ELISA and ELISpot.

IFN-Gamma/ Rat IFN- Gamma ELISA Kit

ELA-E0049r 96 Tests
EUR 1063.2

Anti-IFN gamma PE-Cy7

T7-706-T025 25 tests
EUR 184.8

Anti-IFN gamma PE-Cy7

T7-706-T100 100 tests
EUR 321.6

Anti-IFN gamma PerCP-Cy5.5

T9-706-T025 25 tests
EUR 235.2

Anti-IFN gamma PerCP-Cy5.5

T9-706-T100 100 tests
EUR 422.4

Anti-IFN-gamma alpha antibody

STJ93645 200 µl
EUR 236.4
Description: IFN-gammaRalpha is a protein encoded by the IFNGR1 gene which is approximately 54,4 kDa. IFN-gammaRalpha is localised to the cell membrane and is involved in influenza A, Th17 cell differentiation, interferon gamma signalling, toxoplasmosis and type I interferon signalling pathways. It is a ligand-binding chain of the gamma interferon receptor which also includes IFNGR2. It associates with IFNGR2 to form a receptor for the cytokine interferon gamma. It is also associated with susceptibility to Helicobacter pylori infection. IFN-gammaRalpha is expressed in the nervous system, blood, spleen, lymph node and intestine. Mutations in the IFNGR1 gene result in immunodeficiency 27A and B. STJ93645 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of IFN-gammaRalpha protein.

Anti-IFN-gamma alpha antibody

STJ96760 200 µl
EUR 236.4
Description: Rabbit polyclonal to IFN-gammaRalpha.

Anti-rabbit IFN-gamma antibody

STJ15100000 250 µg
EUR 403.2
Description: This monoclonal antibody enables sensitive and specific detection of rabbit IFN-gamma (IFN-γ) in immunoassays such as ELISA and ELISpot

Anti-rabbit IFN-gamma antibody

STJ15100001 250 µg
EUR 440.4
Description: This monoclonal antibody enables sensitive and specific detection of rabbit IFN-gamma (IFN-γ) in immunoassays such as ELISA, ELISpot and Flow cytometry.

Anti-ferret IFN-gamma antibody

STJ15100004 250 µg
EUR 403.2
Description: This monoclonal antibody enables sensitive and specific detection of ferret IFN-γ in immunoassays such as ELISA and ELISpot.

Anti-ferret IFN-gamma antibody

STJ15100005 250 µg
EUR 440.4
Description: This monoclonal antibody enables sensitive and specific detection of ferret IFN-γ in immunoassays such as ELISA and ELISpot.

Anti-canine IFN-gamma antibody

STJ15100006 250 µg
EUR 403.2
Description: This monoclonal antibody enables sensitive and specific detection of canine (dog) Interferon-gamma (IFN-γ) in immunoassays such as ELISA and ELISpot.

Anti-canine IFN-gamma antibody

STJ15100007 250 µg
EUR 440.4
Description: This monoclonal antibody enables sensitive and specific detection of canine (dog) Interferon-gamma (IFN-γ) in immunoassays such as ELISA and ELISpot.

Anti-equine IFN-gamma antibody

STJ15100010 250 µg
EUR 403.2
Description: This monoclonal antibody enables sensitive and specific detection of equine (horse) Interferon-gamma (IFN-γ) in immunoassays such as ELISA and ELISpot.

Anti-equine IFN-gamma antibody

STJ15100011 250 µg
EUR 440.4
Description: This monoclonal antibody enables sensitive and specific detection of equine (horse) Interferon-gamma (IFN-γ) in immunoassays such as ELISA and ELISpot.

Anti-bovine IFN-gamma antibody

STJ15100012 250 µg
EUR 403.2
Description: This monoclonal antibody enables sensitive and specific detection of bovine IFN-γ in immunoassays such as ELISA and ELISpot.

Anti-bovine IFN-gamma antibody

STJ15100013 250 µg
EUR 440.4
Description: This monoclonal antibody enables sensitive and specific detection of bovine IFN-γ in immunoassays such as ELISA, ELISpot and Flow cytometry.

Anti-cat IFN-gamma antibody

STJ15100018 250 µg
EUR 403.2
Description: This monoclonal antibody enables sensitive and specific detection of cat (feline) IFN-γ in immunoassays such as ELISA and ELISpot.

Anti-cat IFN-gamma antibody

STJ15100019 250 µg
EUR 440.4
Description: This monoclonal antibody enables sensitive and specific detection of cat (feline) IFN-γ in immunoassays such as ELISA and ELISpot.

Anti-mouse IFN-gamma antibody

STJ15100038 250 µg
EUR 403.2
Description: This monoclonal antibody enables sensitive and specific detection of mouse IFN-γ in immunoassays such as ELISA and ELISpot.

Anti-mouse IFN-gamma antibody

STJ15100039 500 µg
EUR 632.4
Description: This monoclonal antibody is recommended for neutralization of mouse IFN-γ bioactivity.

Anti-mouse IFN-gamma antibody

STJ15100040 250 µg
EUR 440.4
Description: This monoclonal antibody enables sensitive and specific detection of mouse IFN-γ in immunoassays such as ELISA and ELISpot.

Anti-Mouse IFN-gamma antibody

STJ16100652 100 µg
EUR 724.8

Anti-Mouse IFN-gamma antibody

STJ16100653 100 µg
EUR 724.8

Anti-rat IFN-gamma antibody

STJ16101138 1 mL
EUR 876

anti-IFN gamma Receptor beta

YF-PA12610 50 ug
EUR 435.6
Description: Mouse polyclonal to IFN gamma Receptor beta

anti-IFN gamma Receptor beta

YF-PA12611 100 ul
EUR 483.6
Description: Rabbit polyclonal to IFN gamma Receptor beta

anti-IFN gamma Receptor beta

YF-PA12612 100 ug
EUR 483.6
Description: Rabbit polyclonal to IFN gamma Receptor beta

Anti-rat IFN gamma Antibody

RP1001 100ug/vial
EUR 400.8

IFN-gamma, human recombinant

4116-100
EUR 307.2

IFN-gamma, human recombinant

4116-1000
EUR 1495.2

IFN-gamma, human recombinant

4116-20
EUR 164.4

Human Interferon-gamma (IFN-gamma) Antibody

33161-05111 150 ug
EUR 313.2

Human Interferon-gamma (IFN-gamma) Antibody

20013-05011 150 ug
EUR 260.4

IFN gamma antibody

70R-12265 200 ug
EUR 483.6
Description: Rabbit polyclonal IFN gamma antibody

IFN gamma antibody

70R-12266 100 ug
EUR 483.6
Description: Rabbit polyclonal IFN gamma antibody

IFN gamma Antibody

5116-200
EUR 379.2

IFN gamma Antibody

5117-100
EUR 379.2

IFN gamma antibody

70-IR18 50 ug
EUR 366
Description: Affinity purified Rabbit polyclonal IFN gamma antibody

IFN gamma antibody

10-7923 1 mg
EUR 516
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10-7924 1 mg
EUR 516
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10-I61a 250 ug
EUR 1363.2
Description: Mouse monoclonal IFN gamma antibody (neutralizing)

IFN gamma antibody

10-I61B 100 ug
EUR 364.8
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10-I61C 500 ug
EUR 327.6
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10-I67A 100 ug
EUR 169.2
Description: Rat monoclonal IFN gamma antibody

IFN gamma antibody

70R-49894 100 ul
EUR 292.8
Description: Purified Polyclonal IFN gamma antibody

IFN gamma antibody

70R-14032 100 ug
EUR 366
Description: Affinity purified Rabbit polyclonal IFN gamma antibody

IFN gamma antibody

70R-13664 100 ug
EUR 438
Description: Affinity purified Rabbit polyclonal IFN gamma antibody

IFN gamma antibody

70R-13665 100 ug
EUR 438
Description: Affinity purified Rabbit polyclonal IFN gamma antibody

IFN gamma protein

30R-1053 100 ug
EUR 268.8
Description: Purified recombinant Human IFN gamma protein

IFN gamma protein

30R-2186 25 ug
EUR 249.6
Description: Purified recombinant Human IFN gamma protein

IFN gamma protein

30R-2267 100 ug
EUR 457.2
Description: Purified recombinant Human IFN gamma protein

IFN gamma protein

30R-2341 20 ug
EUR 182.4
Description: Purified recombinant Human IFN gamma protein

IFN gamma protein

30R-2342 20 ug
EUR 268.8
Description: Purified recombinant Human IFN gamma protein

IFN gamma protein

30R-2343 20 ug
EUR 274.8
Description: Purified recombinant Human IFN gamma protein

IFN gamma protein

30R-3133 50 ug
EUR 308.4
Description: Purified recombinant IFN gamma protein

IFN gamma protein

30R-3159 50 ug
EUR 308.4
Description: Purified recombinant IFN gamma protein

IFN gamma protein

30R-3160 50 ug
EUR 308.4
Description: Purified recombinant IFN gamma protein

IFN gamma antibody

20-IR67 2 x 10^4 units
EUR 548.4
Description: Rabbit polyclonal IFN gamma antibody

IFN gamma protein

30R-AI065 20 ug
EUR 159.6
Description: Purified recombinant Human IFN gamma protein

IFN gamma protein

30R-AI069 100 ug
EUR 327.6
Description: Purified recombinant Human IFN gamma protein

IFN gamma antibody

10R-6643 50 ug
EUR 184.8
Description: Rat monoclonal IFN gamma antibody

IFN gamma antibody

10R-6644 50 ug
EUR 184.8
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10R-6645 50 ug
EUR 184.8
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10R-7733 500 ug
EUR 678
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10R-7764 500 ug
EUR 678
Description: Rat monoclonal IFN gamma antibody

IFN gamma antibody

10R-I101B 500 ug
EUR 327.6
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10R-I101c 500 ug
EUR 548.4
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10R-I157a 500 ug
EUR 716.4
Description: Rat monoclonal IFN gamma antibody

IFN gamma antibody

10R-1882 100 ul
EUR 418.8
Description: Mouse monoclonal IFN gamma antibody

IFN gamma antibody

10R-2118 100 ul
EUR 483.6
Description: Mouse monoclonal IFN gamma antibody

IFN gamma protein

30-1386 500 ug
EUR 470.4
Description: Recombinant IFN gamma protein

IFN gamma Protein

abx060288-100ug 100 ug
EUR 794.4

IFN gamma antibody

70R-IG025 50 ug
EUR 327.6
Description: Affinity purified Goat polyclonal IFN gamma antibody

IFN gamma antibody

70R-IR001 100 ug
EUR 392.4
Description: Affinity purified Rabbit polyclonal IFN gamma antibody

IFN gamma antibody

70R-IR054 50 ug
EUR 327.6
Description: Affinity purified Rabbit polyclonal IFN gamma antibody

rHu IFN-gamma

AK8293-0020 20µg Ask for price

rHu IFN-gamma

AK8293-0100 100µg Ask for price

rHu IFN-gamma

AK8293-1000 1mg Ask for price

IFN-gamma Antibody

BF0395 200ul
EUR 540

IFN-gamma/IFNγ

E21-014 10ug
EUR 411.6

IFN-gamma/IFNγ

E21-746 10ug
EUR 411.6

IFN-gamma/IFNγ

E21-I57 10ug
EUR 411.6

IFN-gamma, Mouse

HY-P7071 10ug
EUR 157.2

IFN-gamma, Rat

HY-P7095 10ug
EUR 157.2

IFN gamma Antibody

R31456 100 ug
EUR 419

IFN gamma, Interferon gamma, rat

RC257-17+A114 20ug
EUR 121.6

Anti-IFN gamma Purified Low Endotoxin

12-705-C100 0.1 mg
EUR 189.6

Mouse Anti-IFN-gamma monoclonal antibody

CABT-BL8852 1.0 mg
EUR 1132.8

Anti-cotton rat IFN-gamma antibody

STJ15100016 250 µg
EUR 403.2
Description: This monoclonal antibody enables sensitive and specific detection of cotton rat IFN-gamma (IFN-γ) in immunoassays such as ELISA and ELISpot.

Anti-cotton rat IFN-gamma antibody

STJ15100017 250 µg
EUR 440.4
Description: This monoclonal antibody enables sensitive and specific detection of cotton rat IFN-gamma (IFN-γ) in immunoassays such as ELISA, ELISpot, and flow cytometry.

Anti-IFN gamma Receptor beta (2D9)

YF-MA13694 100 ug
EUR 435.6
Description: Mouse monoclonal to IFN gamma Receptor beta

IFN-Gamma ab/ Rat IFN- Gamma ab ELISA Kit

ELA-E1716r 96 Tests
EUR 1063.2

Human IFN-gamma(Interferon Gamma) ELISA Kit

STJ150109 1 kit
EUR 494.4
Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of IFN-gamma in human serum, plasma and other biological fluids

Human IFN gamma ELISA Kit

55R-1590 1 kit
EUR 483.6
Description: ELISA kit for detection of IFN gamma in the research laboratory

IFN-gamma (Human) ELISA Kit

E4825-100 96 assays
EUR 697.2

IFN-gamma (CHO-expressed), Human

HY-P7025A 100ug
EUR 294

Recombinant Human IFN-Gamma Protein

PROTP01579-4 100ug
EUR 380.4
Description: IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ species-specific and is biologically active only in human and primate cells. Recombinant human IFN-γ is a 16.8 kDa protein containing 144 amino acid residues.

Antibody for Human IFN gamma

SPC-1297D 0.1ml
EUR 376.8
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is unconjugated.

Antibody for Human IFN gamma

SPC-1297D-A390 0.1ml
EUR 433.2
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to ATTO 390.

Antibody for Human IFN gamma

SPC-1297D-A488 0.1ml
EUR 432
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to ATTO 488.

Antibody for Human IFN gamma

SPC-1297D-A565 0.1ml
EUR 432
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to ATTO 565.

Antibody for Human IFN gamma

SPC-1297D-A594 0.1ml
EUR 432
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to ATTO 594.

Antibody for Human IFN gamma

SPC-1297D-A633 0.1ml
EUR 432
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to ATTO 633.

Antibody for Human IFN gamma

SPC-1297D-A655 0.1ml
EUR 432
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to ATTO 655.

Antibody for Human IFN gamma

SPC-1297D-A680 0.1ml
EUR 432
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to ATTO 680.

Antibody for Human IFN gamma

SPC-1297D-A700 0.1ml
EUR 432
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to ATTO 700.

Antibody for Human IFN gamma

SPC-1297D-ALP 0.1ml
EUR 426
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to Alkaline Phosphatase.

Antibody for Human IFN gamma

SPC-1297D-APC 0.1ml
EUR 430.8
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to APC .

Antibody for Human IFN gamma

SPC-1297D-APCCY7 0.1ml
EUR 518.4
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to APC/Cy7.

Antibody for Human IFN gamma

SPC-1297D-BI 0.1ml
EUR 428.4
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to Biotin.

Antibody for Human IFN gamma

SPC-1297D-DY350 0.1ml
EUR 523.2
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to Dylight 350.

Antibody for Human IFN gamma

SPC-1297D-DY405 0.1ml
EUR 494.4
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to Dylight 405.

Antibody for Human IFN gamma

SPC-1297D-DY488 0.1ml
EUR 471.6
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to Dylight 488.

Antibody for Human IFN gamma

SPC-1297D-DY594 0.1ml
EUR 476.4
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to Dylight 594.

Antibody for Human IFN gamma

SPC-1297D-DY633 0.1ml
EUR 464.4
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to Dylight 633.

Antibody for Human IFN gamma

SPC-1297D-FITC 0.1ml
EUR 423.6
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to FITC.

Antibody for Human IFN gamma

SPC-1297D-HRP 0.1ml
EUR 418.8
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to HRP.

Antibody for Human IFN gamma

SPC-1297D-P594 0.1ml
EUR 440.4
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to PE/ATTO 594.

Antibody for Human IFN gamma

SPC-1297D-PCP 0.1ml
EUR 430.8
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to PerCP.

Antibody for Human IFN gamma

SPC-1297D-RPE 0.1ml
EUR 429.6
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to RPE .

Antibody for Human IFN gamma

SPC-1297D-STR 0.1ml
EUR 430.8
Description: A polyclonal antibody for IFN gamma from Human. The antibody is produced in rabbit after immunization with Human A synthesized peptide derived from human Interferon gamma. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:2000), IHC (1:200). This IFN gamma antibody is conjugated to Streptavidin.

Recombinant Human IFN gamma Protein

R00393 100ug/vial
EUR 352.8

Human IFN gamma Recombinant Protein

R00393-7 5ug/vial
EUR 310.8
Description: IFN-gamma, or type II interferon, is a cytokine that is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Human IFN gamma Recombinant Protein is purified IFN gamma produced in yeast.

Human IFN-gamma ELISA Kit

RK00015 96 Tests
EUR 625.2

IFN gamma, Interferon gamma, murine (mouse)

RC237-17 20ug
EUR 125.26

IFN gamma antibody (biotin)

60R-IG001bt 50 ug
EUR 457.2
Description: Goat polyclonal IFN gamma antibody (biotin)

IFN gamma antibody (biotin)

60R-IR001bt 50 ug
EUR 457.2
Description: Rabbit polyclonal IFN gamma antibody (biotin)

IFN gamma antibody (FITC)

61R-1174 100 ug
EUR 418.8
Description: Mouse monoclonal IFN gamma antibody (FITC)

IFN gamma antibody (PE)

61R-1413 100 ug
EUR 528
Description: Mouse monoclonal IFN gamma antibody (PE)

IFN gamma antibody (biotin)

61R-1660 50 ug
EUR 230.4
Description: Rat monoclonal IFN gamma antibody (biotin)

IFN gamma antibody (biotin)

61R-1661 50 ug
EUR 230.4
Description: Mouse monoclonal IFN gamma antibody (biotin)

IFN gamma antibody (allophycocyanin)

61R-1794 100 ug
EUR 548.4
Description: Mouse monoclonal IFN gamma antibody (allophycocyanin)

IFN gamma antibody (biotin)

61R-I101bBT 500 ug
EUR 548.4
Description: Mouse monoclonal IFN gamma antibody (biotin)

IFN gamma antibody (FITC)

60R-1163 100 ug
EUR 392.4
Description: Rabbit polyclonal IFN gamma antibody (FITC)

IFN gamma ELISA Kit

55R-M1921clb 96 tests
EUR 837.6
Description: Pelikase ELISA kit for detection of Human IFN Gamma in the research laboratory

IFN gamma ELISA Kit

55R-M1933clb 288 tests
EUR 805.2
Description: Pelikase Compact ELISA kit for detection of Human IFN Gamma in the research laboratory

IFN gamma protein (Mouse)

30R-2183 10 ug
EUR 340.8
Description: Purified recombinant Mouse IFN gamma protein

IFN gamma protein (Mouse)

30R-2264 100 ug
EUR 651.6
Description: Purified recombinant Mouse IFN gamma protein

IFN-gamma, rat recombinant

4118-100
EUR 366

IFN-gamma, rat recombinant

4118-1000
EUR 2526

IFN-gamma, rat recombinant

4118-20
EUR 196.8

IFN-gamma, murine recombinant

4117-100
EUR 398.4

IFN-gamma, murine recombinant

4117-1000
EUR 2023.2

IFN-gamma, murine recombinant

4117-20
EUR 202.8

IFN gamma Recombinant Protein

40-277-002mg 0.02 mg
EUR 311.1
Description: IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ species-specific and is biologically active only in human and primate cells. Recombinant human IFN-γ is a 16.7 kDa protein containing 143 amino acid residues.

IFN gamma Recombinant Protein

40-277-01mg 0.1 mg
EUR 437.1
Description: IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ species-specific and is biologically active only in human and primate cells. Recombinant human IFN-γ is a 16.7 kDa protein containing 143 amino acid residues.

IFN gamma Recombinant Protein

40-449-002mg 0.02 mg
EUR 311.1
Description: IFN-gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-gamma receptors are present in most immune cells, which respond to IFN-gamma signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-gamma signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulates the antigen-specific phases of the immune response. Additionally, IFN-gamma stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-gamma species-specific and is biologically active only in human and primate cells. Recombinant murine IFN-gamma is a 15.6 kDa protein containing 134 amino acid residues.

IFN gamma Recombinant Protein

40-449-01mg 0.1 mg
EUR 437.1
Description: IFN-gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-gamma receptors are present in most immune cells, which respond to IFN-gamma signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-gamma signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulates the antigen-specific phases of the immune response. Additionally, IFN-gamma stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-gamma species-specific and is biologically active only in human and primate cells. Recombinant murine IFN-gamma is a 15.6 kDa protein containing 134 amino acid residues.

IFN gamma Recombinant Protein

40-472-002mg 0.02 mg
EUR 311.1
Description: IFN-gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-gamma receptors are present in most immune cells, which respond to IFN-gamma signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-gamma signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-gamma stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-gamma is species-specific and is biologically active only in human and primate cells. Recombinant rat IFN-gamma is a 15.6 kDa protein containing 135 amino acid residues.

IFN gamma Recombinant Protein

40-472-01mg 0.1 mg
EUR 437.1
Description: IFN-gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-gamma receptors are present in most immune cells, which respond to IFN-gamma signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-gamma signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-gamma stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-gamma is species-specific and is biologically active only in human and primate cells. Recombinant rat IFN-gamma is a 15.6 kDa protein containing 135 amino acid residues.

Canine IFN-gamma Antibody

33344-05111 150 ug
EUR 313.2

IFN gamma 1 protein

30R-AI068 20 ug
EUR 327.6
Description: Purified recombinant Human IFN gamma 1 protein

IFN gamma protein (Mouse)

30R-AI070x 100 ug
EUR 327.6
Description: Purified recombinant Mouse IFN gamma protein

IFN gamma 2 protein

30R-AI150 20 ug
EUR 327.6
Description: Purified recombinant Human IFN gamma 2 protein

IFN gamma Recombinant Protein

91-012 0.05 mg
EUR 374.1
Description: IFN gamma is the major interferon produced by mitogenically or antigenically stimulated lymphocytes. It is structurally different from type I interferon and its major activity is immunoregulation. It has been implicated in the expression of class II histocompatibility antigens in cells that do not normally produce them, leading to autoimmune disease. Interferon gamma is produced mainly byT-cells and natural killer cells activated by antigens, mitogens, or alloantigens. It is produced by lymphocytes expressing the surface antigens CD4 and CD8. IFN gamma synthesis is induced by IL-2, FGF-basic, and EGF.

IFN gamma Recombinant Protein

91-591 0.05 mg
EUR 374.1
Description: Mouse Ifng is a secreted protein which belongs to the type I I (or gamma) interferon family. IFNG is produced by lymphocytes and activated by specific antigens or mitogens. In addition to having antiviral activity, IFNG also has important immunoregulatory functions. It is a potent activator of macrophages and has antiproliferative effects on transformed cells. It can potentiate the antiviral and antitumor effects of the type I interferons. Genetic variation in IFNG is associated with the risk of aplastic anemia (AA) which is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis.

IFN gamma Recombinant Protein

92-362 0.05 mg
EUR 437.1
Description: IFN gamma is the major interferon produced by mitogenically or antigenically stimulated lymphocytes. It is structurally different from type I interferon and its major activity is immunoregulation. It has been implicated in the expression of class II histocompatibility antigens in cells that do not normally produce them, leading to autoimmune disease. Interferon gamma is produced mainly byT-cells and natural killer cells activated by antigens, mitogens, or alloantigens. It is produced by lymphocytes expressing the surface antigens CD4 and CD8. IFN gamma synthesis is induced by IL-2, FGF-basic, and EGF.

IFN-Gamma (IFNG) Antibody

abx139543-01mg 0.1 mg
EUR 427.2

IFN-Gamma (IFNG) Antibody

abx139544-01mg 0.1 mg
EUR 427.2

IFN-Gamma (IFNG) Antibody

abx139545-01mg 0.1 mg
EUR 427.2

IFN-Gamma (IFNG) Antibody

abx139546-01mg 0.1 mg
EUR 427.2

IFN-gamma Antibody (FITC)

abx139547-100tests 100 tests
EUR 510

HS negatively affected the rate of cleavage and blastocyst, in all groups of HS. On Day 7, all HS-treated embryos showed a decrease IFNT gene and protein expression, whereas the reactive oxygen species increased compared with controls. In conclusion, early embryonic development is compromised because of the higher temperatures during in vitro oocyte maturation, fertilization, and / or the zygote stage has diminished IFNT expression and increased reactive oxygen species in cattle.

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